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CAS No.: 80-77-3
Name: Chlormezanone
Molecular Structure:
Molecular Structure of 80-77-3 (Chlormezanone)
Formula: C11H12 Cl N O3 S
Molecular Weight: 273.74
Synonyms: 4H-1,3-Thiazin-4-one,2-(p-chlorophenyl)tetrahydro-3-methyl-, 1,1-dioxide (6CI,7CI,8CI); (?à)-Chlormezanone; (?à)-Fenarol;2-(4-Chlorophenyl)-3-methyl-4-metathiazanone-1,1-dioxide;2-(p-Chlorophenyl)-3-methyl-1,3-perhydrothiazin-4-one 1,1-dioxide;2-(p-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide;2-(p-Chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide; Alinam;Banabin-Sintyal; Chlormethazanone; Chlormethazone; Chlormezanone;Dichloromezanone; Fenarol; Lobak; Mio-Sed; Muskel Trancopal; NSC 169108;Phenarol; Rexan; Rilansyl; Rilaquil; Rilasol; Rilassol; Supotran; Suprotran;Tanafol; Trancopal; Trancote; Transanate; dl-Chlormezanone
EINECS: 201-307-4
Density: 1.391g/cm3
Melting Point: 114 °C
Boiling Point: 534.5oC at 760 mmHg
Flash Point: 277.1oC
Safety: Poison by intraperitoneal and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by ingestion: dilation of the pupils, ataxia (loss of muscle coordination), and coma. When heated to decomposition it emits very toxic fumes of SOx, NOx, and Cl.
PSA: 62.83000
LogP: 2.63420
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    chlormezanone CAS:80-77-3 the cheapest price

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  • Chlormezanone;1,1-dioxide-2-(4-chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one

  • Casno:

    80-77-3

    Chlormezanone;1,1-dioxide-2-(4-chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one

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  • Chlormezanone

  • Casno:

    80-77-3

    Chlormezanone

    Min.Order: 10 Gram

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Chemistry

IUPAC Name: 2-(4-Chlorophenyl)-3-methyl-1,1-dioxo-1,3-thiazinan-4-one
Product Name: 2-(4-Chlorophenyl)-3-methyl-1,1-dioxo-1,3-thiazinan-4-one
The MF of Chlormezanone (CAS NO.80-77-3) is C11H12ClNO3S.

                         
The MW of Chlormezanone (CAS NO.80-77-3) is 273.74.
Synonyms of Chlormezanone (CAS NO.80-77-3): (±)-Chlormezanone ; 2-(4-Chlorophenyl)-3-methyl-1,3-thiazinan-4-one 1,1-dioxide ; 2-(4-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide ; 2-(p-Chlorophenyl)perhydro-3-methyl-1,3-thiazin-4-one 1,1-dioxide ; 4H-1,3-Thiazin-4-one, 2- (4-chlorophenyl)tetrahydro-3-methyl-, 1,1-dioxide ; Dichloromethazanone ; Lobak
Form: A white crystalline powder
Index of Refraction: 1.58 
EINECS: 201-307-4
Density: 1.391 g/ml 
Flash Point: 277.1 °C
Boiling Point: 534.5 °C
Melting Point: 114 °C
Merck: 2106

Uses

  Chlormezanone (CAS NO.80-77-3) is used as weak antipsychotic. With a calm, stable and central role in muscle relaxation.also used for fear of mental stress, chronic fatigue, anxiety, excitement, and irritation caused by certain diseases such as not sleeping. Due to the importance of muscle relaxation, with the analgesic can be used for back acid, neck hard, bone pain, spinal and limb pain and rheumatoid joint pain.

Production

Raw materials: 4-Chlorobenzaldehyde-->3-Mercaptopropionic acid
Preparation Products: whitener WG for wool-->Ketamine hydrochloride

Toxicity Data With Reference

1.    

orl-man TDLo:157 mg/kg:EYE,CNS

    BMJOAE    British Medical Journal. 292 (1986),732.
2.    

orl-rat LD50:605 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 130 (1961),280.
3.    

ipr-rat LD50:370 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 17 (1967),242.
4.    

orl-mus LD50:600 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 9 (1975),601.
5.    

ipr-mus LD50:570 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 17 (1967),242.
6.    

scu-mus LD50:322 mg/kg

    APTOA6    Acta Pharmacologica et Toxicologica. 19 (1962),247.
7.    

orl-dog LD50:500 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 1 (1959),168.
8.    

ipr-dog LD50:500 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 1 (1959),168.
9.    

ipr-gpg LD50:600 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 1 (1959),168.

Safety Profile

Poison by intraperitoneal and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by ingestion: dilation of the pupils, ataxia (loss of muscle coordination), and coma. When heated to decomposition it emits very toxic fumes of SOx, NOx, and Cl.Safety information of Chlormezanone (CAS NO.80-77-3):
RTECS  XJ1050000