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CAS No.: | 8053-39-2 |
---|---|
Name: | Horse chestnut, Aesculus hippocastanum, ext. |
Molecular Structure: | |
Formula: | N/A |
Molecular Weight: | 0 |
Synonyms: | Horse chestnut, aesculus hippocastanum, ext.;Aesculus hippocastanum (horse chestnut) seed extract;Horse chestnut; |
EINECS: | 232-497-7 |
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Product Name: Triterpene saponins mixture from aesculus hippocastonum L. (CAS NO.8053-39-2)
Mol File: 8053-39-2.mol
Einecs: 232-497-7
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
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guinea pig | LD50 | intravenous | 37mg/kg (37mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960. | |
guinea pig | LD50 | intravenous | 940mg/kg (940mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960. | |
guinea pig | LD50 | oral | 1120mg/kg (1120mg/kg) | Drugs in Japan Vol. 6, Pg. 398, 1982. | |
mouse | LD50 | intraperitoneal | 6700ug/kg (6.7mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982. | |
mouse | LD50 | intraperitoneal | 55mg/kg (55mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: PLEURAL THICKENING | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 45, 1980. |
mouse | LD50 | intravenous | 14400ug/kg (14.4mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960. | |
mouse | LD50 | intravenous | 1377mg/kg (1377mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960. | |
mouse | LD50 | oral | 164mg/kg (164mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982. | |
mouse | LD50 | oral | 990mg/kg (990mg/kg) | Drugs in Japan Vol. 6, Pg. 398, 1982. | |
mouse | LD50 | subcutaneous | 38500ug/kg (38.5mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982. | |
rabbit | LD50 | intravenous | 30mg/kg (30mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960. | |
rabbit | LD50 | intravenous | 400mg/kg (400mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960. | |
rabbit | LD50 | oral | 1530mg/kg (1530mg/kg) | Drugs in Japan Vol. 6, Pg. 398, 1982. | |
rat | LD50 | intraperitoneal | 10100ug/kg (10.1mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982. | |
rat | LD50 | intraperitoneal | 13750mg/kg (13750mg/kg) | Drugs in Japan Vol. 6, Pg. 399, 1982. | |
rat | LD50 | intravenous | 62500ug/kg (62.5mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960. | |
rat | LD50 | intravenous | 1450mg/kg (1450mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960. | |
rat | LD50 | oral | 833mg/kg (833mg/kg) | Yakkyoku. Pharmacy. Vol. 33, Pg. 335, 1982. | |
rat | LD50 | oral | 2150mg/kg (2150mg/kg) | Drugs in Japan Vol. 6, Pg. 398, 1982. | |
rat | LD50 | subcutaneous | 150mg/kg (150mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982. |
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. See also SAPONIN.
Triterpene saponins mixture from aesculus hippocastonum L. , its CAS NO. is 8053-39-2, the synonyms are Horse chestnut, aesculus hippocastanum, ext. ; Aesculus hippocastanum (horse chestnut) seed extract ; Horse chestnut ; Triterpene saponins mixture from aesculus hippocastonum L. ; Buckeye ; Chestnut, horse .