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832-92-8

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Basic Information
CAS No.: 832-92-8
Name: MESCALINE HYDROCHLORIDE
Article Data: 2
Molecular Structure:
Molecular Structure of 832-92-8 (MESCALINE HYDROCHLORIDE)
Formula: C11H17 N O3 . Cl H
Molecular Weight: 247.722
Synonyms: Benzeneethanamine,3,4,5-trimethoxy-, hydrochloride (9CI); Phenethylamine, 3,4,5-trimethoxy-, hydrochloride(8CI); 2-(3,4,5-Trimethoxyphenyl)ethylamine hydrochloride;3,4,5-Trimethoxyphenethylamine hydrochloride; Mescaline hydrochloride;Mescaline hydrochloride salt
EINECS: 212-626-3
Melting Point: 180-182°C
Boiling Point: 312.1 °C at 760 mmHg
Flash Point: 145.8 °C
Hazard Symbols: HarmfulXn
Risk Codes: 22
Safety: Poison by intravenous, intraperitoneal, and subcutaneous routes. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also MESCALINE.
PSA: 53.71000
LogP: 2.71590
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Chemistry

The IUPAC name of Mescaline hydrochloride (CAS NO.832-92-8): 2-(3,4,5-Trimethoxyphenyl)ethanamine hydrochloride 
Synonyms: 3,4,5-Trimethoxy-beta-phenylethylamine hydrochloride ; 3,4,5-Trimethoxyphenethylamine hydrochloride ; Mescaline hydrochloride ; Mescaline hydrochloride salt 
CAS: 832-92-8
EINECS: 212-626-3 
Molecular Formula: C11H18ClNO3
Formula Weight: 247.72 g/mol
Molecular Structure:

Flash Point: 145.8 °C 
Boiling Point: 312.1 °C at 760 mmHg 
Melting point: 180-182°C 
Chemical Properties Off-White Solid

Uses

The usage of Mescaline hydrochloride (CAS NO.832-92-8):
Psychotomimetic alkaloid isolated from peyote (mescal buttons), the flowering heads of Lophophora williamsii (Lemaire). Controlled substance (hallucinogen)

Toxicity Data With Reference

The toxicity of Mescaline hydrochloride (CAS NO.832-92-8):

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 54mg/kg (54mg/kg) BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: NAUSEA OR VOMITING
Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.
guinea pig LD50 intraperitoneal 328mg/kg (328mg/kg)   Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.
monkey LD50 intravenous 130mg/kg (130mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: ATAXIA
Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.
mouse LD50 intraperitoneal 212mg/kg (212mg/kg)   Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.
mouse LD50 intravenous 110mg/kg (110mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR
Toxicology and Applied Pharmacology. Vol. 45, Pg. 49, 1978.
mouse LD50 oral 800mg/kg (800mg/kg)   Helvetica Chimica Acta. Vol. 49, Pg. 403, 1966.
rat LD50 intraperitoneal 132mg/kg (132mg/kg)   Toxicology and Applied Pharmacology. Vol. 25, Pg. 299, 1973.
rat LDLo subcutaneous 320mg/kg (320mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 71, Pg. 62, 1941.

Safety Profile

The Hazard Codes of Mescaline hydrochloride (CAS NO.832-92-8): HarmfulXnToxicTFlammableF
Risk Statements:R22:Harmful if swallowed. R23/24/25:Toxic by inhalation, in contact with skin and if swallowed. R36/38:Irritating to eyes and skin.R11:Highly flammable.R39/23/24/25: Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed   
Safety Statements: S22:Do not breathe dust. S36:Wear suitable protective clothing. S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37:Wear suitable protective clothing and gloves. S24:Avoid contact with skin. S16:Keep away from sources of ignition. S7:Keep container tightly closed.
RIDADR: UN 1230 3/PG 2
WGK Germany: 3
RTECS: SI2800000
Poison by intravenous, intraperitoneal, and subcutaneous routes. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also MESCALINE.