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84-36-6

Basic Information
CAS No.: 84-36-6
Name: SYROSINGOPINE
Molecular Structure:
Molecular Structure of 84-36-6 (SYROSINGOPINE)
Formula: C35H42 N2 O11
Molecular Weight: 666.725
Synonyms: 3b,20a-Yohimban-16b-carboxylic acid, 18b-hydroxy-11,17a-dimethoxy-, methyl ester,4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester) (8CI); Reserpicacid, methyl ester, ester with syringic acid, ethyl carbonate (6CI);Carbethoxysyringoyl methylreserpate; Isotense; Londomin; Methylcarbethoxysyringoyl reserpate; Methyl reserpate ester of syringic acid ethylcarbonate; NSC 77030; Raunova; Seniramin; Singoserp; Siringina; Su 3118;Syringic acid ethyl carbonate ester with methyl reserpate; Syringopine;Syrosingopin; Syrosingopine
Density: 1.35g/cm3
Melting Point: 175°C
Boiling Point: 795oC at 760 mmHg
Flash Point: 434.6oC
Safety: Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
PSA: 144.08000
LogP: 4.63570
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Chemistry

EINECS: 201-527-0 
Empirical Formula: C35H42N2O11
Molecular Weight: 666.7148 g/mol
Melting point: 175 °C
Structure of Syrosingopine (CAS NO.84-36-6):
                    
Product Category of Syrosingopine (CAS NO.84-36-6): Alkaloids

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 101mg/kg (101mg/kg)   Drugs in Japan Vol. 6, Pg. 365, 1982.
mouse LD50 oral 1293mg/kg (1293mg/kg)   Drugs in Japan Vol. 6, Pg. 365, 1982.
mouse LD50 subcutaneous 281mg/kg (281mg/kg)   Drugs in Japan Vol. 6, Pg. 365, 1982.
rat LD50 intraperitoneal 286mg/kg (286mg/kg)   Drugs in Japan Vol. 6, Pg. 365, 1982.
rat LD50 intravenous 50mg/kg (50mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 119, Pg. 245, 1959.
rat LD50 oral > 2gm/kg (2000mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 386, 1975.
rat LD50 subcutaneous > 2gm/kg (2000mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 386, 1975.

Safety Profile

Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition Syrosingopine (CAS NO.84-36-6) emits toxic fumes of NOx.

Specification

 Syrosingopine , its cas register number is 84-36-6. It also can be called Syringopine ; 18-O-(3,5-Dimethoxy-4-
ethoxycarbonyloxybenzoyl)eserpsaeuremethylester ; Reserpic acid, methyl ester, ester with 4-hydroxy-3,5-
dimethoxybenzoic acid ethyl carbonate ; and Methyl 18beta-hydroxy-11,17alpha-dimethoxy-3beta,20alpha-
yohimban-16beta-carboxylate 4-hydroxy .