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| CAS No.: | 87-10-5 |
|---|---|
| Name: | 3,5,4'-TRIBROMOSALICYLANILIDE |
| Article Data: | 8 |
| Molecular Structure: | |
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| Formula: | C13H8 Br3 N O2 |
| Molecular Weight: | 449.924 |
| Synonyms: | Salicylanilide,3,4',5-tribromo- (6CI,8CI); 3,4',5-Tribromosalicylanilide;3,5-Dibromo-6-hydroxybenz-p-bromanilide;3,5-Dibromo-N-(4-bromophenyl)-2-hydroxybenzamide; 3,5-Dibromosalicylic acidp-bromoanilide; Agramed; NSC 20526; Sherstat TBS; TBS; Temasept II; TemaseptIV; Tempasept II; Tribromsalan; Trisanil; Trisanyl; Tuasal 100; Tuasol; VancideTBS; WR 34912 |
| Density: | 1.135g/cm3 |
| Melting Point: | 223-224°C |
| Boiling Point: | 367.7°C at 760 mmHg |
| Flash Point: | 146.3°C |
| Hazard Symbols: | A suspected carcinogen. Use in cosmetics prohibited (FDA). |
| Risk Codes: | 22 |
| Safety: | Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of Br− and NOx. See also BROMIDES. |
| PSA: | 49.33000 |
| LogP: | 5.00500 |
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- Total:21 Page 1 of 1 1
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Chemistry
Chemistry informtion about 3,5,4'-Tribromosalicylanilide (CAS NO.87-10-5) is:
IUPAC Name: 3,5-Dibromo-N-(4-Bromophenyl)-2-Hydroxybenzamide
Synonyms: 3,4',5-Tribromosalicylanide And 4,5-Dibromosalicylanide Mixtures ; 3,4',5-Tribromo-Salicylanilid ; 3,5-Dibromo-N-(4-Bromophenyl)-2-Hydroxy-Benzamid ; 3,5-Dibromo-N-(4-Bromophenyl)-2-Hydroxybenzamide ; 3,5-Dibromo-N-(4-Bromophenyl)-2-Hydroxy-Benzamide ; 3,5-Dibromosalicylic Acid P-Bromoanilide ; 3,5-Dibrono-N-(4-Bromophenyl)-2-Hydroxyben-Zamide,3,4',5-Tribromosalicylanilide ; Agramed
Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts ; Organics
MF: C13H8Br3NO2
MW: 449.92
EINECS: 201-723-6
Density: 2.089 g/cm3
Melting Point: 223-224°C
Flash Point: 201.2 °C
Boiling Point: 409.1 °C at 760 mmHg
Vapour Pressure: 2.82E-07 mmHg at 25°C
Enthalpy of Vaporization: 68.69 kJ/mol
Merck: 9616
Following is the molecular structure of 3,5,4'-Tribromosalicylanilide (CAS NO.87-10-5) is:
Uses
3,5,4'-Tribromosalicylanilide (CAS NO.87-10-5) was used for the manufacture of sterile medicated soap (neutral soap product containing the 0.3-0.5%), and used for prevention and control skin diseases, hospital disinfectant washing liquid. It also can be used as preservatives in cosmetics.
Production
Raw materials is Salicylanilide .
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LD50 | oral | 410mg/kg (410mg/kg) | Industrial Medicine and Surgery. Vol. 39, Pg. 56, 1970. | |
| rat | LD50 | subcutaneous | 1120mg/kg (1120mg/kg) | U.S.S.R. Patent Document. Vol. #0413949, |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of Br− and NOx. See also BROMIDES.
Risk Statements:
R22:Harmful if swallowed.
Safety Statements:
S20:When using, do not eat or drink.and smoke.
RTECS: VN8925000
Specification
3,5,4'-Tribromosalicylanilide (CAS NO.87-10-5) is a colorless to light brown needle-like crystal. It can soluble in dimethylformamide, hot acetone and slightly soluble in ethanol, but, it insoluble in water.