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89-52-1

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Basic Information
CAS No.: 89-52-1
Name: N-Acetylanthranilic acid
Article Data: 173
Molecular Structure:
Molecular Structure of 89-52-1 (N-Acetylanthranilic acid)
Formula: C9H9NO3
Molecular Weight: 179.175
Synonyms: Anthranilicacid, N-acetyl- (6CI,7CI,8CI);1-Acetylamino-2-carboxybenzene;2-(Acetylamino)benzoic acid;2-Acetamidobenzoic acid;2-Carboxyacetanilide;NSC 17831;NSC 4000;o-(Acetylamino)benzoic acid;o-(N-Acetylamino)benzoic acid;o-Acetamidobenzoic acid;
EINECS: 201-914-4
Density: 1.326 g/cm3
Melting Point: 184-187 °C(lit.)
Boiling Point: 422.8 °C at 760 mmHg
Flash Point: 209.5 °C
Solubility: slightly soluble in water
Appearance: solid
Hazard Symbols: HarmfulXn,IrritantXi
Risk Codes: 22-36/37/38
Safety: 36-37/39-26
PSA: 66.40000
LogP: 1.41620
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Chemistry

Chemical Name: N-Acetylanthranilic acid
IUPAC NAME: 2-acetamidobenzoic acid
CAS No.: 89-52-1
EINECS: 201-914-4
RTECS: CB2455000
RTECS Class: Drug
Molecular Formula: C9H9NO3
Molecular Weight: 179.17 g/mol
Density: 1.326 g/cm3
Melting Point: 184-187 °C(lit.)
Flash Point: 209.5 °C
Boiling Point: 422.8 °C at 760 mmHg
2-ACETAMIDOBENZOIC ACID(89-52-1) is slightly soluble in water,and it is stable under normal temperatures and pressures.but incompatible with strong oxidizing agents; strong acids; strong bases; strong reducing agents.Following is the structure of 2-ACETAMIDOBENZOIC ACID(89-52-1):

                      
The chemical synonymous of 2-ACETAMIDOBENZOIC ACID(89-52-1) are 2-(acetylamino)-benzoicaci;2-carboxyacetanilide;acetylanthranilicacid;Lappaconiticacid;n-acetylaminobenzoicacid;n-acetyl-anthranilicaci;n-acetylanthranillicacid;o-acetamidoanthranilic.

Uses

2-ACETAMIDOBENZOIC ACID(89-52-1) is used for pharmaceutical intermediates, for the production of non-barbiturate hypnotic methaqualone.and it is used in the manufacture of the controlled substances and is important to the manufacture of the substances.

Production

Product Categories about 2-ACETAMIDOBENZOIC ACID(89-52-1) are Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;API intermediates;Pharmaceutical Intermediate.

Toxicity Data With Reference

1.   

orl-mus LD50:1114 mg/kg

   FRPSAX    Farmaco, Edizione Scientifica. 38 (1983),847.
2. mouse     LD50     oral    1114mg/kg (1114mg/kg)   BEHAVIORAL: ANALGESIA  
Farmaco,Edizione Scientifica. Vol. 38, Pg. 847, 1983.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx.
Hazard Note: Irritant
Hazard Codes:
    Xn: Harmful
    Xi: Harmful 
Risk Statements about 2-ACETAMIDOBENZOIC ACID(89-52-1):
    R22 Harmful if swallowed.
    R36/37/38 Very toxic by inhalation, in contact with skin and if swallowed.
Safety Statements about 2-ACETAMIDOBENZOIC ACID(89-52-1):
    S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    S36 Wear suitable protective clothing.
    S37/39 Wear suitable gloves and eye/face protection.

Specification

1. Storage: Store in a cool, dry place. Keep container closed when not in use.
2. Handling: Avoid contact with eyes, skin, and clothing. Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not ingest or inhale.
3. Personal Protection: Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
4. Fire Fighting: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.