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971-74-4

Basic Information
CAS No.: 971-74-4
Name: 3-(2-AMINOETHYL)-5-HYDROXYINDOLE CREATININE SULFATE COMPLEX
Molecular Structure:
Molecular Structure of 971-74-4 (3-(2-AMINOETHYL)-5-HYDROXYINDOLE CREATININE SULFATE COMPLEX)
Formula: C10H12N2O•C4H7N3O•H2O4S•H2O
Molecular Weight: 387.417
Synonyms: 3-(2-aminoethyl)-indol-5-ocompd.withcreatininesulfate;3-(2-aminoethyl)indol-5-ol,creatininesulfate;5-htcreatininesulfate;creatinine,sulfate,compd.with3-(2-aminoethyl)indol-5-ol(1:1:1);creatinine,sulfate,compd.with3-(2-aminoethyl)indole-5-ol(1:1:1),monohyd;serotincreatininesulfate;5-HYDROXYTRYPTAMINE CREATININE SULFATE;5-HYDROXYTRYPTAMINE CREATININE SULFATE COMPLEX
Density: g/cm3
Melting Point: ~220 °C (dec.)
Boiling Point: 416.1°Cat760mmHg
Flash Point: 205.4°C
Hazard Symbols:
Risk Codes: 63-20/21/22
Safety: Poison by subcutaneous and intravenous routes. Moderately toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. See also SULFATES. When heated to decomposition it emits very toxic fumes of SOx and NOx.
PSA: 203.71000
LogP: 1.34990
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Chemistry

Empirical Formula: C14H21N5O6S
Molecular Weight: 387.4114 g/mol
EINECS: 213-539-3
Flash Point: 205.4 °C
Enthalpy of Vaporization: 69.52 kJ/mol
Boiling Point: 416.1 °C at 760 mmHg
Vapour Pressure: 1.63E-07 mmHg at 25 °C
Solubility: 0.1 M HCl: Solutions should be freshly prepared.
Form: Powder
Color: White to off-white
Structure of 5-Hydroxytryptamine creatinine sulfate (CAS NO.971-74-4):
                    
IUPAC Name of 5-Hydroxytryptamine creatinine sulfate (CAS NO.971-74-4): 3-(2-Aminoethyl)-1H-indol-5-ol; 2-amino-3-methyl-4H-imidazol-5-one ; Sulfuric acid

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intravenous 28mg/kg (28mg/kg) LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION Journal of Pharmaceutical Sciences. Vol. 57, Pg. 1543, 1968.
mouse LD50 intraperitoneal 405mg/kg (405mg/kg)   Yakugaku Zasshi. Journal of Pharmacy. Vol. 94, Pg. 1620, 1974.
mouse LD50 intravenous 352mg/kg (352mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 80, 1952.
mouse LD50 subcutaneous > 1997mg/kg (1997mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 80, 1952.
rat LD50 intravenous 66mg/kg (66mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 80, 1952.
rat LD50 subcutaneous 257mg/kg (257mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 80, 1952.

Consensus Reports

EPA Genetic Toxicology Program.

Safety Profile

Poison by subcutaneous and intravenous routes. Moderately toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. See also SULFATES. When heated to decomposition it emits very toxic fumes of SOx and NOx.
Hazard Codes of 5-Hydroxytryptamine creatinine sulfate (CAS NO.971-74-4): HarmfulXn
Risk Statements: 63-20/21/22 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R63:Possible risk of harm to the unborn child.
Safety Statements: 36/37-24/25-22 
S22:Do not breathe dust. 
S24/25:Avoid contact with skin and eyes. 
S36/37:Wear suitable protective clothing and gloves.

Specification

 5-Hydroxytryptamine creatinine sulfate ,its cas register number is 971-74-4. It also can be called 3-(2-Aminoethyl)indol-5-ol 2-imino-1-methylimidazolidin-4-one sulphate (1:1) ; 2-Amino-1,5-dihydro-1-methyl-4H-imidazol-4-one cpd with 3-(2-aminoethyl)-1H-indol-5-ol sulfate ; and Indol-5-ol, 3-(2-aminoethyl)-, compd. with creatinine sulfate .