10488-68-3Relevant articles and documents
Preparation method 2 - (4 -hydroxy -2 - oxo -1 - pyrrolidinyl) acetamide (by machine translation)
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Paragraph 0030; 0032; 0033; 0037; 0039; 0040, (2019/07/29)
The invention relates to the field, organic synthesis and medicine technology. In particular, the invention provides a method for preparing 2 - (4 -hydroxy -2 - oxo -1 - pyrrolidinyl) acetamide, which uses methyl 4 - chloroacetoacetate as a starting material, condenses, crystallizes and crystallizes after carbonyl reduction to obtain a target product, and the total yield is approximately unitz 90% is left and right. The method optimizes the reaction steps by improving the synthesis route, namely the 2 - (4 - hydroxyl -2 - oxo -1 - pyrrolidinyl) acetamide, and shortens the production cycle, and shortens the production cycle. The production cost, as well as the emission. The method is cheap and easy to obtain, simple and convenient to operate, low in impurities, high in yield, and particularly suitable for industrial production. (by machine translation)
Reduction processes biocatalyzed by Vigna unguiculata
Bizerra, Ayla M.C.,Gonzalo, Gonzalo de,Lavandera, Ivan,Gotor-Fernandez, Vicente,de Mattos, Marcos Carlos,de Oliveira, Maria da Conceicao F.,Lemos, Telma L.G.,Gotor, Vicente
experimental part, p. 566 - 570 (2010/08/06)
Whole cells from the Brazilian beans feijao de corda (Vigna unguiculata) have been employed as biocatalysts in different bioreduction processes. Good to excellent selectivities can be obtained in the reduction of aromatic and aliphatic ketones, as well as β-ketoesters, depending on the conversions and the chemoselectivity on the substrate structure. This biocatalyst was also able to reduce the nitro moiety of different aromatic nitro compounds, showing as well enoate reductase activity, and chemoselectively catalyzing the double bond reduction of 4-phenyl-3-buten-2-one with moderate conversion.
Tandem concurrent processes: One-pot single-catalyst biohydrogen transfer for the simultaneous preparation of enantiopure secondary alcohols
Bisogno, Fabricio R.,Lavandera, Ivan,Kroutil, Wolfgang,Gotor, Vicente
supporting information; experimental part, p. 1730 - 1732 (2009/07/11)
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