107036-62-4 Usage
General Description
5-fluoro-2',3'-dideoxycytidine is a synthetic analog of the nucleoside cytidine that is used as an antiviral agent. It is a potent inhibitor of the replication of retroviruses, including HIV, and is used in the treatment of HIV/AIDS. The chemical works by interfering with the normal function of the viral enzyme reverse transcriptase, which is essential for the replication of the virus. This disruption ultimately halts the production of new viral particles and helps to control the progression of the infection. 5-fluoro-2',3'-dideoxycytidine has shown efficacy in reducing viral load and improving the immune function in patients with HIV, making it an important component of antiretroviral therapy.
Check Digit Verification of cas no
The CAS Registry Mumber 107036-62-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,0,3 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 107036-62:
(8*1)+(7*0)+(6*7)+(5*0)+(4*3)+(3*6)+(2*6)+(1*2)=94
94 % 10 = 4
So 107036-62-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H12FN3O3/c10-6-3-13(9(15)12-8(6)11)7-2-1-5(4-14)16-7/h3,5,7,14H,1-2,4H2,(H2,11,12,15)/t5-,7+/m0/s1
107036-62-4Relevant articles and documents
NMR studies of pyrimidinic nucleosides derived from 2,3-dideoxy-d-ribose with inhibitory activity on LINE-1 mobility
Banuelos-Sanchez, Guillermo,Franco-Montalban, Francisco,Tamayo, Juan A.
, p. 118 - 125 (2019/11/28)
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Potent Anti-AIDS Drugs. 2',3'-Dideoxycytidine Analogues
Kim, Chong-Ho,Marquez, Victor E.,Broder, Samuel,Mitsuya, Hiroaki,Driscoll, John S.
, p. 862 - 866 (2007/10/02)
5-Substituted 2',3'-dideoxycytidine analogues have been synthesized and evaluated in vitro for their capabilities to protect T4+ lymphocytes from the cytopathic effects of the HTLV-III/LAV (HIV) virus, the causative agent of acquired immunodefi
