1190-79-0Relevant articles and documents
An alternative pathway for production of acetonitrile: Ruthenium catalysed aerobic dehydrogenation of ethylamine
Corker, Emily C.,Mentzel, Uffe V.,Mielby, Jerrik,Riisager, Anders,Fehrmann, Rasmus
, p. 928 - 933 (2013)
The oxidative synthesis of acetonitrile from ethylamine was studied using a supported ruthenium catalyst. The reaction was conducted in both batch and flow processes and high conversions (over 85%) were achieved in both cases. Selectivity of both reactions was improved by optimisation of reaction conditions, achieving over 90% selectivity in the batch process and 80% selectivity in the continuous flow process. The use of a selective solid catalyst that utilises a feedstock that can be derived from biomass, dioxygen as the oxidant and water as the solvent represents a new, green route for the independent and efficient production of acetonitrile.
Mechanistic insights into the oxidative dehydrogenation of amines to nitriles in continuous flow
Corker, Emily C.,Ruiz-Martínez, Javier,Riisager, Anders,Fehrmann, Rasmus
, p. 5008 - 5015 (2015/11/03)
The oxidative dehydrogenation of various aliphatic amines to their corresponding nitrile compounds using RuO2/Al2O3 catalysts in air was successfully applied to a continuous flow reaction. Conversions of amines (up to >99%) and yields of nitriles (up to 77%) varied depending on reaction conditions and the amine utilised. The presence of water was found to be important for the activity and stability of the RuO2/Al2O3 catalyst. The Hammett relationship and in situ infrared spectroscopy were applied to divulge details about the catalytic mechanism of the oxidative dehydrogenation of amines over RuO2/Al2O3 catalysts.
Matrix-IR spectroscopic investigations of the thermolysis and photolysis of diazoamides
Wentrup, Curt,Bibas, Herve,Kuhn, Arvid,Mitschke, Ullrich,McMills, Mark C.
, p. 10705 - 10717 (2013/11/19)
Matrix photolysis of N,N-dialkyldiazoacetamides 1a-d at 7-10 K results in either the formation of C-H insertion products (in case of N,N-dimethyl and N,N-diethyl diazoamides) or almost exclusive Wolff rearrangement to ketenes (in the case of the cyclic di
