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121148-01-4

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121148-01-4 Usage

Description

(2S,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate is a complex organic compound with the molecular formula C13H26N2O4. It is a clear, liquid solution that belongs to the category of amines and is a member of the pyrrolidine family, characterized by a five-membered saturated ring with one nitrogen atom and four carbon atoms. As a stereospecific compound, it has a unique configuration where the 2nd and 4th positions are organically substitutable and identified as S, indicating a left-handed orientation. The t-butyl group, an alkyl substituent derived from tert-butyl alcohol, further distinguishes its structure. Primarily used for research purposes, this molecule is valuable in chemical synthesis and pharmaceutical research.

Uses

Used in Chemical Synthesis:
(2S,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate is used as a key intermediate in the synthesis of various complex organic molecules. Its unique structure and functional groups make it a versatile building block for creating new compounds with specific properties and applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (2S,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate is used as a starting material or a precursor in the development of new drugs. Its unique stereochemistry and functional groups can be exploited to design and synthesize novel pharmaceutical agents with improved efficacy and selectivity.
Used in Research Applications:
(2S,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate is used as a research tool in various scientific studies. Its unique properties and reactivity can be explored to gain insights into the fundamental aspects of organic chemistry, stereochemistry, and molecular interactions. This knowledge can be applied to develop new synthetic methods, improve existing processes, and discover innovative applications in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 121148-01-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,1,4 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 121148-01:
(8*1)+(7*2)+(6*1)+(5*1)+(4*4)+(3*8)+(2*0)+(1*1)=74
74 % 10 = 4
So 121148-01-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H20N2O4/c1-11(2,3)17-10(15)13-6-7(12)5-8(13)9(14)16-4/h7-8H,5-6,12H2,1-4H3/t7-,8-/m1/s1

121148-01-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate

1.2 Other means of identification

Product number -
Other names 1-O-tert-butyl 2-O-methyl (2S,4S)-4-aminopyrrolidine-1,2-dicarboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:121148-01-4 SDS

121148-01-4Relevant articles and documents

MELANOCORTIN-4 RECEPTOR AGONISTS

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, (2021/05/15)

The present invention relates to a compound exhibiting excellent agonist activity against melanocortin receptors. More specifically, the present invention relates to a compound of Formula 1, a pharmaceutical composition comprising the compound as an activ

Superior HIV-1 TAR Binders with Conformationally Constrained R52 Arginine Mimics in the Tat(48–57) Peptide

Bhosle, Govind S.,Kharche, Shalmali,Kumar, Santosh,Sengupta, Durba,Maiti, Souvik,Fernandes, Moneesha

, p. 220 - 226 (2018/01/22)

We report a 100-fold increase in binding affinity of the Tat(48–57) peptide to HIV-1 transcriptional activator-responsive element (TAR) RNA by replacing Arg52, an essential and critical residue for Tat's specific binding, with (2S,4S)-4-guanidinoproline. The resulting αTat1M peptide is a far superior binder than γTat1M, a peptide containing another conformationally constrained arginine mimic, (2S,4S)-4-amino-N-(3-guanidinopropyl)proline, or even the control Tat peptide (CtrlTat) itself. Our observations are supported by circular dichroism (CD), isothermal titration calorimetry (ITC), gel electrophoresis and UV spectroscopy studies. Molecular dynamics simulations suggest increased interactions between the more compact αTat1M and TAR RNA, relative to CtrlTat. The CD signature of the RNA itself remains largely unchanged upon binding of the peptides. The Tat mimetics further have better cell uptake properties than the control Tat peptide, thus increasing their potential application as specific TAR-binding molecules.

An ionic liquid containing L-proline moiety as highly efficient and recyclable chiral organocatalyst for Michael addition

Li, Jiang,Li, Xia Bing,Ma, Sha Sha,Liu, Juan,Li, Ben Hao,Li, Bao Lin

, p. 1259 - 1264 (2016/08/12)

A novel chiral ionic liquid containing proline moiety was synthesized. It can be used as a highly efficient and recyclable chiral organocatalyst for Michael addition of cyclohexanone with (E)-β-nitroalkenes in methanol at room temperature. The Michael add

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