121148-01-4 Usage
Description
(2S,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate is a complex organic compound with the molecular formula C13H26N2O4. It is a clear, liquid solution that belongs to the category of amines and is a member of the pyrrolidine family, characterized by a five-membered saturated ring with one nitrogen atom and four carbon atoms. As a stereospecific compound, it has a unique configuration where the 2nd and 4th positions are organically substitutable and identified as S, indicating a left-handed orientation. The t-butyl group, an alkyl substituent derived from tert-butyl alcohol, further distinguishes its structure. Primarily used for research purposes, this molecule is valuable in chemical synthesis and pharmaceutical research.
Uses
Used in Chemical Synthesis:
(2S,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate is used as a key intermediate in the synthesis of various complex organic molecules. Its unique structure and functional groups make it a versatile building block for creating new compounds with specific properties and applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (2S,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate is used as a starting material or a precursor in the development of new drugs. Its unique stereochemistry and functional groups can be exploited to design and synthesize novel pharmaceutical agents with improved efficacy and selectivity.
Used in Research Applications:
(2S,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate is used as a research tool in various scientific studies. Its unique properties and reactivity can be explored to gain insights into the fundamental aspects of organic chemistry, stereochemistry, and molecular interactions. This knowledge can be applied to develop new synthetic methods, improve existing processes, and discover innovative applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 121148-01-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,1,4 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 121148-01:
(8*1)+(7*2)+(6*1)+(5*1)+(4*4)+(3*8)+(2*0)+(1*1)=74
74 % 10 = 4
So 121148-01-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H20N2O4/c1-11(2,3)17-10(15)13-6-7(12)5-8(13)9(14)16-4/h7-8H,5-6,12H2,1-4H3/t7-,8-/m1/s1
121148-01-4Relevant articles and documents
MELANOCORTIN-4 RECEPTOR AGONISTS
-
Paragraph 91-94, (2021/05/15)
The present invention relates to a compound exhibiting excellent agonist activity against melanocortin receptors. More specifically, the present invention relates to a compound of Formula 1, a pharmaceutical composition comprising the compound as an activ
Antibacterial and anti-TB tat-peptidomimetics with improved efficacy and half-life
Bhosle, Govind S.,Nawale, Laxman,Yeware, Amar M.,Sarkar, Dhiman,Fernandes, Moneesha
, p. 358 - 369 (2018/05/22)
Non-natural antimicrobial peptides are ideal as next-generation antibiotics because of their ability to circumvent the problems of drug resistance and in vivo instability. We report novel all-α- and α,γ-mixed Tat peptide analogues as potential antibacterial and anti-TB agents. These peptides have broad spectrum antibacterial activities against Gram-positive (MICs 0.61 ± 0.03 to 1.35 ± 0.21 μM with the peptide γTatM4) and Gram-negative (MICs 0.71 ± 0.005 to 1.26 ± 0.02 μM with γTatM4) bacteria and are also effective against active and dormant forms of Mycobacterium tuberculosis, including strains that are resistant to rifampicin and isoniazid. The introduction of the non-natural amino acids of the study in the Tat peptide analogues results in increased resistance to degradation by proteolysis, significantly increasing their half-life. The peptides appear to inhibit bacteria by a membrane disruption mechanism, and have only a low cytotoxic effect on mammalian cells.
An ionic liquid containing L-proline moiety as highly efficient and recyclable chiral organocatalyst for Michael addition
Li, Jiang,Li, Xia Bing,Ma, Sha Sha,Liu, Juan,Li, Ben Hao,Li, Bao Lin
, p. 1259 - 1264 (2016/08/12)
A novel chiral ionic liquid containing proline moiety was synthesized. It can be used as a highly efficient and recyclable chiral organocatalyst for Michael addition of cyclohexanone with (E)-β-nitroalkenes in methanol at room temperature. The Michael add
