124937-73-1 Usage
Description
3-(2-Methoxy-5-methylphenyl)-3-phenyl propanol, also known as 2-Methoxy-5-methyl-γ-phenylbenzenepropanol, is a chemical compound with a unique molecular structure that features a propanol group attached to a phenyl ring with a methoxy and methyl substitution pattern. 3-(2-Methoxy-5-methylphenyl)-3-phenyl propanol is related to Tolterodine (T535795), a muscarinic receptor antagonist, and has potential applications in the pharmaceutical industry due to its structural similarity.
Uses
Used in Pharmaceutical Industry:
3-(2-Methoxy-5-methylphenyl)-3-phenyl propanol is used as an active pharmaceutical ingredient for the treatment of urinary incontinence. Its structural similarity to Tolterodine, a muscarinic receptor antagonist, allows it to potentially modulate the muscarinic receptors in the bladder, thereby improving the symptoms of urinary incontinence.
Used in Drug Development:
In addition to its direct application in treating urinary incontinence, 3-(2-Methoxy-5-methylphenyl)-3-phenyl propanol can also be used as a starting material or a structural template for the development of new drugs targeting muscarinic receptors. Its unique molecular features may provide a basis for designing more effective and selective muscarinic receptor antagonists or agonists for various therapeutic applications.
Used in Research and Development:
3-(2-Methoxy-5-methylphenyl)-3-phenyl propanol can be utilized in research and development for understanding the structure-activity relationship of muscarinic receptor modulators. By studying the interactions of this compound with muscarinic receptors, researchers can gain insights into the design of more potent and selective drugs for treating conditions related to muscarinic receptor dysregulation.
Check Digit Verification of cas no
The CAS Registry Mumber 124937-73-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,9,3 and 7 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 124937-73:
(8*1)+(7*2)+(6*4)+(5*9)+(4*3)+(3*7)+(2*7)+(1*3)=141
141 % 10 = 1
So 124937-73-1 is a valid CAS Registry Number.
InChI:InChI=1/C22H31NO.ClH/c1-16(2)23(17(3)4)14-13-20(19-9-7-6-8-10-19)21-15-18(5)11-12-22(21)24;/h6-12,15-17,20,24H,13-14H2,1-5H3;1H/t20-;/m1./s1
124937-73-1Relevant articles and documents
Iron-catalyzed regioselective transfer hydrogenative couplings of unactivated aldehydes with simple alkenes
Zheng, Yan-Long,Liu, Yan-Yao,Wu, Yi-Mei,Wang, Yin-Xia,Lin, Yu-Tong,Ye, Mengchun
supporting information, p. 6315 - 6318 (2016/05/24)
An FeBr3-catalyzed reductive coupling of various aldehydes with alkenes that proceeds through a direct hydride transfer pathway has been developed. With iPrOH as the hydrogen donor under mild conditions, previously challenging coupling reactions of unactivated alkyl and aryl aldehydes with simple alkenes, such as styrene derivatives and α-olefins, proceeded smoothly to furnish a diverse range of functionalized alcohols with complete linear regioselectivity. The reductive coupling of various aldehydes and alkenes through a direct hydride transfer pathway can be catalyzed by FeBr3. With isopropanol as the hydrogen donor, previously challenging coupling reactions of unactivated alkyl and aryl aldehydes with simple alkenes, such as styrene derivatives and α-olefins, proceeded smoothly to furnish a diverse range of functionalized alcohols with complete linear regioselectivity.
PROCESS FOR THE PREPARATION OF (R)-2-(3-DIISOPROPYLAMINO)-1-PHENYLPROPYL)-4METHYLPHENOL AND SALTS THEREOF
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, (2012/03/08)
The present invention relates to an improved process for the preparation of Tolterodine or salts thereof, which comprises the use of 3-(2-methoxy-5-methylphenyl)-3-phenylpropyl methane sulfonate.
A PROCESS FOR THE PREPARATION OF TOLTERODINE TARTRATE
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Paragraph 157-164, (2010/09/03)
The present invention relates to provide a process for the preparation of (+)-(R)-Tolterodine-L-tartrate, comprises a step of aminating hydroxyl protected 3-(2-methoxy-5-methylphenyl)-3-phenyl propanol of formula (V) with diisopropylamine in the presence of water to obtain N, N-diisopropyl-3-(2-methoxy-5-methylphenyl)-3-phenylpropyl amine of formula (VI).
