129446-71-5 Usage
Description
(4S)-4-BENZYL-L-GLUTAMIC ACID is an amino acid derivative featuring a glutamic acid molecule with a benzyl group attached to the fourth carbon atom. As a chiral molecule, the (S)-stereoisomer is the biologically relevant form, which has been investigated for its pharmacological activities, such as acting as an agonist for the metabotropic glutamate receptors and modulating the central nervous system. Its unique structure and properties render it a promising candidate for drug development and for elucidating the biological roles of glutamic acid derivatives in the body.
Uses
Used in Pharmaceutical Development:
(4S)-4-BENZYL-L-GLUTAMIC ACID is used as a pharmacological agent for its potential role as an agonist for the metabotropic glutamate receptors, which are involved in various physiological processes and are implicated in neurological disorders. Its agonistic properties may contribute to the development of new therapeutics targeting these receptors.
Used in Central Nervous System Modulation:
(4S)-4-BENZYL-L-GLUTAMIC ACID is used as a modulator in the central nervous system, where it may influence neurotransmission and synaptic plasticity. Its effects on the CNS could be leveraged for the treatment of neurological conditions associated with glutamate dysregulation.
Used in Drug Development Research:
(4S)-4-BENZYL-L-GLUTAMIC ACID serves as a key molecule in research aimed at understanding the biological functions of glutamic acid derivatives. Its unique structure allows scientists to explore the mechanisms of action and potential therapeutic applications of this class of compounds in the body.
Used in Chemical Synthesis:
(4S)-4-BENZYL-L-GLUTAMIC ACID can be used as a building block in the synthesis of more complex molecules with potential biological activities. Its chiral nature and functional groups make it a versatile component in the creation of novel pharmaceuticals and bioactive compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 129446-71-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,4,4 and 6 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 129446-71:
(8*1)+(7*2)+(6*9)+(5*4)+(4*4)+(3*6)+(2*7)+(1*1)=145
145 % 10 = 5
So 129446-71-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO4/c13-10(12(16)17)7-9(11(14)15)6-8-4-2-1-3-5-8/h1-5,9-10H,6-7,13H2,(H,14,15)(H,16,17)/t9-,10-/m0/s1
129446-71-5Relevant articles and documents
(2S,3S)-2-Amino-3-(2,2-diphenylethyl)pentanedioic acid selective group 2 metabotropic glutamate receptor antagonist
Escribano, Ana,Ezquerra, Jesus,Pedregal, Concepcion,Rubio, Almudena,Yruretagoyena, Belen,Baker, S. Richard,Wright, Rebecca A.,Johnson, Bryan G.,Schoepp, Darryle D.
, p. 765 - 770 (2007/10/03)
(2S,4S)-2-Amino-4-(4,4-diphenylbut-1-yl)-pentane-1,5-dioic acid 1m, is a novel metabotropic glutamate receptor (mGluR) antagonist with insignificant ionotropic affinity. It is a selective antagonist of negatively-coupled cAMP-linked mGluRs with no effect
