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13062-61-8

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13062-61-8 Usage

Uses

Different sources of media describe the Uses of 13062-61-8 differently. You can refer to the following data:
1. 4-Hydroxy-3-methoxy Amphetamine is a metabolite of 3,4-methylenedioxymethamphetamine (MDMA). 4-Hydroxy-3-methoxy Amphetamine was significantly less potent than MDMA at inhibiting [3H]noradrenaline and [3H]5-HT transport in mammalian cell lines.
2. Labelled analogue of 4-Hydroxy-3-methoxy Amphetamine, a metabolite of 3,4-methylenedioxymethamphetamine (MDMA). 4-Hydroxy-3-methoxy Amphetamine was significantly less potent than MDMA at inhibiting [ 3H]noradrenaline and [3H]5-HT transport in mammalian cell lines.

Check Digit Verification of cas no

The CAS Registry Mumber 13062-61-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,6 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 13062-61:
(7*1)+(6*3)+(5*0)+(4*6)+(3*2)+(2*6)+(1*1)=68
68 % 10 = 8
So 13062-61-8 is a valid CAS Registry Number.

13062-61-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Hydroxy-3-methoxy Amphetamine Hydrochloride

1.2 Other means of identification

Product number -
Other names 4-(2-aminopropyl)-2-methoxyphenol,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13062-61-8 SDS

13062-61-8Downstream Products

13062-61-8Relevant articles and documents

Comparative potencies of 3,4-methylenedioxymethamphetamine (MDMA) analogues as inhibitors of [3H]noradrenaline and [3H]5-HT transport in mammalian cell lines

Montgomery,Buon,Eibauer,Guiry,Keenan,McBean

, p. 1121 - 1130 (2008/03/13)

Background and purpose: Illegal 'ecstasy' tablets frequently contain 3,4-methylenedioxymethamphetamine (MDMA)-like compounds of unknown pharmacological activity. Since monoamine transporters are one of the primary targets of MDMA action in the brain, a number of MDMA analogues have been tested for their ability to inhibit [3H]noradrenaline uptake into rat PC12 cells expressing the noradrenaline transporter (NET) and [3H]5-HT uptake into HEK293 cells stably transfected with the 5-HT transporter (SERT). Experimental approach: Concentration-response curves for the following compounds at both NET and SERT were determined under saturating substrate conditions: 4-hydroxy-3-methoxyamphetamine (HMA), 4-hydroxy-3-methoxymethamphetamine (HMMA), 3,4-methylenedioxy-N-hydroxyamphetamine (MDOH), 2,5-dimethoxy-4- bromophenylethylamine (2CB), 3,4-dimethoxymethamphetamine (DMMA), 3,4-methylenedioxyphenyl-2-butanamine (BDB), 3,4-methylenedioxyphenyl-N-methyl- 2-butanamine (MBDB) and 2,3-methylenedioxymethamphetamine (2,3-MDMA). Key results: 2,3-MDMA was significantly less potent than MDMA at SERT, but equipotent with MDMA at NET. 2CB and BDB were both significantly less potent than MDMA at NET, but equipotent with MDMA at SERT. MBDB, DMMA, MDOH and the MDMA metabolites HMA and HMMA, were all significantly less potent than MDMA at both NET and SERT. Conclusions and implications: This study provides an important insight into the structural requirements of MDMA analogue affinity at both NET and SERT. It is anticipated that these results will facilitate understanding of the likely pharmacological actions of structural analogues of MDMA.