13066-51-8Relevant articles and documents
Studies on the alkylation of 3-methyl-3-buten-1-ol dianion: An efficient synthesis of 3-methylene-1-alkanols including a San Jose scale sex pheromone
Yong, Kelvin H.,Lotoski, John A.,Chong, J. Michael
, p. 8248 - 8251 (2001)
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Alexakis,A. et al.
, p. 471 - 485 (1975)
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Copper-catalyzed enantioselective 1,2-borylation of 1,3-dienes
Liu, Yangbin,Fiorito, Daniele,Mazet, Clément
, p. 5284 - 5288 (2018/06/21)
A highly enantioselective Cu-catalyzed borylation of 2-substituted 1,3-dienes is reported. The use of a chiral phosphanamine ligand is essential in achieving high chemo-, regio-, diastereo- and enantioselectivity. It provides access to a variety of homoallylic boronates in consistently high yield and enantiomeric excess with 2-aryl and 2-heteroaryl 1,3-dienes as well as sterically demanding 2-alkyl 1,3-dienes. Preliminary investigations based on a non-linear effect study point to a mechanism involving more than one metal center.
Chelation versus Non-Chelation Control in the Stereoselective Alkenyl sp2 C?H Bond Functionalization Reaction
Liang, Qiu-Ju,Yang, Chao,Meng, Fei-Fan,Jiang, Bing,Xu, Yun-He,Loh, Teck-Peng
supporting information, p. 5091 - 5095 (2017/04/24)
A hydroxy group chelation-assisted stereospecific oxidative cross-coupling reaction between alkenes was developed under mild reaction conditions. In the presence of palladium catalyst, the alkenes tethered with hydroxy functionality can couple efficiently with electron-deficient alkenes to form the corresponding multi-substituted olefin products. The hydroxy group on the substrate could play dual roles in reaction, acting as the directing group for alkenyl C?H bond activation and controlling the stereoselectivity of the products.