13277-24-2Relevant articles and documents
P(III)-Mediated Cascade C-N/C-S Bond Formation: A Protocol towards the Synthesis of N,S-Heterocycles and Spiro Compounds
Polina, Saibabu,Putta, V. P. Rama Kishore,Gujjarappa, Raghuram,Singh, Virender,Pujar, Prasad Pralhad,Malakar, Chandi C.
supporting information, p. 431 - 445 (2020/12/07)
A P(III)-mediated entry towards construction of C?N/C?S bond has been devised. The developed heterocyclization method was exercised for the synthesis of a diverse range of N,S-heterocycles and related spiro molecules. P(NMe2)3 revealed the maximum efficacies under the aerobic reaction conditions and a spectrum of bis-nucleophiles, and isothiocyanates were tolerated well to serve the access of manifold immense molecules. (Figure presented.).
Synthesis and biological activity of N-aroyl-N′-substituted thiourea derivatives
Zhang,Wei,Gao
, p. 3099 - 3105 (2007/10/03)
A series of N-aroyl-N′-substituted thiourea derivatives have been prepared in good to excellent yields under the condition of solid-liquid phase transfer catalysis using polyethylene glycol-400(PEG-400) as the catalyst. The products have been characterize
REACTIONS OF N-BENZOYL ISOTHIOCYANATE WITH ANTHRANILIC ACID AND METHYL ANTHRANILATE
Kavalek, Jaromir,Kotyk, Milan,El Bahaie, Said,Sterba, Vojeslav
, p. 246 - 255 (2007/10/02)
N-Benzoyl-N'-(2-carboxy- and -2-methoxycarbonylphenyl)thioureas have been obtained by the reaction of N-benzoyl isothiocyanate with anthranilic acid and methyl anthranilate, respectively.Kinetics of cyclization of these compounds into 2-mercapto-3,4-dihydro-4-quinazolone have been studied in water and in methanol.In the base-catalyzed cyclization of N-benzoyl-N'-(2-carboxyphenyl)thiourea the proper cyclization is preceded by solvolysis of the benzoyl group.In the case of N-benzoyl-N'-(2-methoxycarbonylphenyl)thiourea the reaction rate is limited by the base-catalyzed cyclization of the starting benzoyl derivative; the benzoyl group is split off in a subsequent rapid step.