13512-57-7 Usage
Description
BOC-ASN-OBZL, also known as Boc-Asparagine-O-Benzyl, is a synthetic compound commonly utilized in the field of organic chemistry and pharmaceutical research. It is a protected derivative of the naturally occurring amino acid asparagine, featuring a benzyl group (Bzl) attached to the amino group and a tert-butyloxycarbonyl (BOC) group protecting the carboxylic acid group. BOC-ASN-OBZL is known for its role in the synthesis of various biologically active molecules and its potential applications in drug development.
Uses
Used in Pharmaceutical Research:
BOC-ASN-OBZL is used as a synthetic building block for the development of novel pharmaceutical compounds. Its protected structure allows for selective deprotection and functionalization, enabling the creation of diverse drug candidates with potential therapeutic applications.
Used in Organic Chemistry:
In the field of organic chemistry, BOC-ASN-OBZL serves as a versatile reactant for the synthesis of complex organic molecules. Its protected functional groups facilitate controlled reactions, minimizing side reactions and improving the overall yield of the desired products.
Used in Metabolite Isolation:
BOC-ASN-OBZL is used as a reactant to isolate new metabolites from pks+ E. coli mutants that are missing an essential biosynthetic enzyme. This application highlights its utility in understanding the metabolic pathways and the role of specific enzymes in bacterial metabolism, which can be crucial for the development of new antibiotics or other therapeutic agents targeting bacterial infections.
Check Digit Verification of cas no
The CAS Registry Mumber 13512-57-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,5,1 and 2 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 13512-57:
(7*1)+(6*3)+(5*5)+(4*1)+(3*2)+(2*5)+(1*7)=77
77 % 10 = 7
So 13512-57-7 is a valid CAS Registry Number.
InChI:InChI=1/C16H22N2O5/c1-16(2,3)23-15(21)18-12(9-13(17)19)14(20)22-10-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H2,17,19)(H,18,21)
13512-57-7Relevant articles and documents
An improved synthesis of β-cyano- l -alanine esters and amides
Wang, Guoxin,Chen, Longjian,Cai, Xiaodan,Li, Zigang,Luo, Ming
, p. 309 - 312 (2016/01/20)
We have developed a novel, mild, efficient, and scalable protocol for the synthesis of N-protected β-cyano-l-alanine esters or -amides from N-protected l-asparagin. This protocol avoided the use of toxic or unpleasant reagents and was easy to operate in laboratory.
Erratum: Isolation of a metabolite from the pks island provides insights into colibactin biosynthesis and activity (Organic Letters (2015) 17:6 (1545-1548) DOI: 10.1021/acs.orglett.5b00432)
Brotherton, Carolyn A.,Wilson, Matthew,Byrd, Gary,Balskus, Emily P.
supporting information, p. 2294 - 2294 (2015/05/13)
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Synthesis of imidazolidin-2-one-4-carboxylate and of (tetrahydro)pyrimidin- 2-one-5-carboxylate via an efficient modification of the Hofmann rearrangement
Angelici, Gaetano,Contaldi, Simone,Lynn Green, Sarah,Tomasini, Claudia
experimental part, p. 1849 - 1852 (2008/10/09)
A mild and efficient methodology for the rearrangement of protected asparagine and protected glutamine is reported; good results are obtained with a wide selection of protecting groups. The Royal Society of Chemistry.
