13879-32-8 Usage
General Description
"1,1'-[methylenebis(oxyethane-1,2-diyloxy)]bisbenzene" is a chemical compound that consists of benzene rings connected by a central chain of ethylene oxide units. 1,1'-[methylenebis(oxyethane-1,2-diyloxy)]bisbenzene is commonly used as a crosslinking agent in the production of epoxy resins and polyurethane foams. It also serves as a precursor in the synthesis of various chemical compounds, including surfactants, detergents, and pharmaceuticals. Additionally, it is utilized as a stabilizer in plastic materials and as an additive in personal care products. However, it is important to handle this chemical with care, as it can cause skin irritation and allergic reactions in some individuals. Overall, "1,1'-[methylenebis(oxyethane-1,2-diyloxy)]bisbenzene" has a variety of industrial applications and is a valuable building block in chemical synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 13879-32-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,8,7 and 9 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 13879-32:
(7*1)+(6*3)+(5*8)+(4*7)+(3*9)+(2*3)+(1*2)=128
128 % 10 = 8
So 13879-32-8 is a valid CAS Registry Number.
13879-32-8Relevant articles and documents
Synthesis and Antiviral Evaluation of 1-[(2-Phenoxyethyl)oxymethyl] and 6-(3,5-Dimethoxybenzyl) Analogues of HIV Drugs Emivirine and TNK-651
El-Brollosy,Loddo
, p. 181 - 188 (2016/05/02)
Novel emivirine analogues 6a, b were synthesized by reacting chloromethyl ethyl ether with 5-ethyl/isopropyl-6-(3,5-dimethoxybenzyl)uracils 5e, f. On the other hand, A series of new TNK-651 analogues 10a-f substituted at N-1 with phenoxyethoxymethyl moiety was prepared on treatment of the corresponding uracils 5a-f with bis(phenoxyethoxy)methane (9). The newly synthesized non-nucleosides were tested for antiviral activity against wild type HIV-1 IIIB as well as the resistant strains N119 (Y181C), A17 (K103N+Y181C), and the triple mutant EFVR (K103R+V179D+P225H) in MT-4 cells. Most of the tested compounds showed good activities. Among them 6-(3,5-dimethylbenzyl)-5-ethyl-1-[(2-phenoxyethyl)oxymethyl]uracil (10c) and 6-(3,5-dimethylbenzyl)-5-isopropyl-1-[(2-phenoxyethyl)oxymethyl]uracil (10d) that showed inhibitory potency higher than emivirine against both wild type HIV-1 and the tested mutant strains, as well as higher activity than efavirenz against EFVR.
