15055-81-9 Usage
Description
METHYL ISOXAZOLE-5-CARBOXYLATE, also known as 5-Isoxazolecarboxylic Acid Methyl Ester, is an organic compound that serves as a crucial synthetic intermediate in the pharmaceutical industry. It is characterized by its isoxazole ring and carboxylate ester functional groups, which contribute to its reactivity and potential applications in medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
METHYL ISOXAZOLE-5-CARBOXYLATE is used as a reagent for the synthesis of pyridine derivatives, which act as integrase inhibitors and antiviral agents. These derivatives are essential in the development of treatments for various viral infections, including HIV.
Used in Cancer Treatment:
METHYL ISOXAZOLE-5-CARBOXYLATE is also a useful synthetic intermediate in the preparation of pyrazolopyrimidine derivatives. These compounds are valuable in the prevention and treatment of cancer, as they can target specific cellular pathways and mechanisms involved in tumor growth and progression.
Check Digit Verification of cas no
The CAS Registry Mumber 15055-81-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,0,5 and 5 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 15055-81:
(7*1)+(6*5)+(5*0)+(4*5)+(3*5)+(2*8)+(1*1)=89
89 % 10 = 9
So 15055-81-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H5NO3/c1-8-5(7)4-2-3-6-9-4/h2-3H,1H3
15055-81-9Relevant articles and documents
Carboxylation of C-H bonds using N -heterocyclic carbene gold(I) complexes
Boogaerts, Ine I. F.,Nolan, Steven P.
supporting information; experimental part, p. 8858 - 8859 (2010/08/21)
A highly efficient [(NHC)AuI]-based (NHC = N-heterocyclic carbene) catalytic system for the carboxylation of aromatic and heteroaromatic C-H bonds was developed. The significant base strength of the Au-OH species is at the origin of the activation process and permits the facile functionalization of C-H bonds without the use of other organometallic reagents.
Pyrazolo[1,5-A]pyrimidine derivatives and methods of use thereof
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Page/Page column 51, (2010/11/28)
The present invention relates to pyrazolo[1,5-a]pyrimidine derivatives, compositions comprising an effective amount of a pyrazolo[1,5-a]pyrimidine derivative and methods for treating or preventing cancer, comprising administering to a subject in need thereof an effective amount of a pyrazolo[1,5-a]pyrimidine derivative.
