15100-75-1 Usage
Description
t-Butyl 3-phenyl-L-alaninate hydrochloride is a crystalline derivative of L-Phenylalanine, an essential amino acid. It is characterized by its unique chemical structure, which includes a tert-butyl ester group and a phenylalanine moiety. tert-Butyl 3-phenyl-L-alaninate hydrochloride exhibits valuable chemical properties that make it suitable for various applications across different industries.
Uses
Used in Pharmaceutical Industry:
t-Butyl 3-phenyl-L-alaninate hydrochloride is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications, particularly in the treatment of neurological disorders and other conditions that may benefit from the modulation of specific neurotransmitter systems.
Used in Chemical Synthesis:
In the field of organic chemistry, t-Butyl 3-phenyl-L-alaninate hydrochloride serves as a valuable building block for the synthesis of complex organic molecules. Its reactivity and structural features make it an attractive candidate for the development of novel chemical entities with potential applications in various industries, including materials science, agrochemistry, and pharmaceuticals.
Used in Research and Development:
Due to its unique chemical properties and structural features, t-Butyl 3-phenyl-L-alaninate hydrochloride is also used in research and development settings. It can be employed as a model compound for studying various chemical reactions and mechanisms, as well as for the development of new synthetic methodologies and techniques.
Used in Analytical Chemistry:
The crystalline nature of t-Butyl 3-phenyl-L-alaninate hydrochloride makes it a useful compound for analytical chemistry applications. It can be used as a reference material for the calibration of analytical instruments, such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS) systems, ensuring accurate and reliable measurements in various analytical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 15100-75-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,1,0 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 15100-75:
(7*1)+(6*5)+(5*1)+(4*0)+(3*0)+(2*7)+(1*5)=61
61 % 10 = 1
So 15100-75-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H19NO2.ClH/c1-13(2,3)16-12(15)11(14)9-10-7-5-4-6-8-10;/h4-8,11H,9,14H2,1-3H3;1H
15100-75-1Relevant articles and documents
A Simple Chiral Cu(II) Complex as an Effective Phase-Transfer Catalyst for the Enantioselective Alkylation of Dissymmetric Glycinate Ketimines
Bafqiren, Hanane,Zouihri, Hafid,Gmouh, Said,Jamal Eddine, Jamal
, p. 944 - 950 (2015/11/16)
Catalytic asymmetric benzylation of a dissymmetric tert-butylglycinate ketimine, incorporating 1-naphthyl and phenyl groups as the Schiff base substituents, under phase-transfer conditions was investigated. It was interesting to note that the sense of asymmetric induction of the alkylation of Z-imine stereoisomer is opposite to that of the corresponding E stereoisomer with a similar degree of enantioselectivity. More interestingly, the chiral Cu(II) complex of the Schiff base derived from (R)-2-phenylglycinol and 2-hydroxy-1-naphthaldehyde was found to catalyze the same reaction under solid-liquid conditions with comparable enantioselectivity (up to 60% ee) with respect to known cinchona alkaloid catalysts. The solvent/base-system parameter was shown to control the optimal catalytic activity. Chirality 27:944-950, 2015.
Chiral salen-metal complexes as novel catalysts for the asymmetric synthesis of α-amino acids under phase transfer catalysis conditions
Belokon, Yuri N,North, Michael,Churkina, Tatiana D,Ikonnikov, Nikolai S,Maleev, Victor I
, p. 2491 - 2498 (2007/10/03)
Chiral salen-metal complexes have been tested as catalysts for the C-alkylation of Schiff's bases of alanine and glycine esters with alkyl bromides under phase-transfer conditions (solid sodium hydroxide, toluene, ambient temperature, 1-10 mol% of the catalyst). The best catalyst, which was derived from a Cu(II) complex of (1R, 2R or 1S,2S)-[N,N′-bis(2′-hydroxybenzylidene)]-1,2-diaminocyclohexane, gave α-amino and α-methyl-α-amino acids with enantiomeric excesses of 70-96%.
