151135-82-9Relevant articles and documents
Synthetic method and application of natural product Kanzonol C and derivatives thereof
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, (2019/12/02)
The invention discloses a synthetic method and application of a natural product Kanzonol C and derivatives thereof. The structural formula (I) and (II) are shown in the specification: compared with anatural product Kanzonol C, the obtained novel isopenten
Synthetic methods for prenylated chalcones and pyranochalcones
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, (2017/04/27)
The inventors of the present invention invented a simple and effective way to synthesize compounds 1-9 of natural prenylated chalcones and pyrano chalcones by using Claisen-Schmidt condensation as a main step. In addition, an anti-inflammatory effect of synthetic compounds was evaluated in RAW 264.7 macrophages which were stimulated with a lipopolysaccharide. As a result, chalcone compounds having prenyl groups in a ring A (an acetophenone part) show weak inhibition or no inhibition on the generation of nitrogen oxide while chalcones (5, 6, 8, and 9) having no prenyl groups in the ring A show normal or good activity, and have no cytotoxicity.COPYRIGHT KIPO 2017