1314539-20-2

Upstream product

• 65490-08-6 2-hydroxy-4-(methoxymethoxy)acetophenone 
• 503-60-6 3,3-dimethyl-allyl chloride 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 

Downstream Products

• 952647-84-6 (E)-1-(2-hydroxy-4-(methoxymethoxy)-5-(3-methylbut-2-en-1-yl)phenyl)-3-(4-(methoxymethoxy)phenyl)prop-2-en-1-one 
• 1314539-32-6 (E)-1-(2-hydroxy-4-(methoxymethoxy)-3,5-bis(3-methylbut-2-en-1-yl)phenyl)-3-(4-(methoxymethoxy)phenyl)prop-2-en-1-one 
• 961-29-5 isoliquirtigenin 
• 54676-49-2 isobavachalcone 
• 124775-22-0 1-<2-Hydroxy-4-(methoxymethoxy)phenyl>-3-<4-(methoxymethoxy)phenyl>prop-2-en-1-on 
• 1314539-23-5 4,4'-bis(methoxymethoxy)-2'-prenyloxychalcone 
• 934247-88-8 7,4'-dimethoxymethoxy-6-(3,3-dimethylallyl)-flavanone 
• 948307-21-9 2-hydroxy-4,4’-dimethoxy methyl ether-5-isopentenyl chalcone 
• 78316-27-5 (+/-)-bavachin 
• 99217-72-8 2-hydroxy-5-(3,3-dimethylallyl)-4-methoxymethyloxyacetophenone 
• 34211-25-1 derricin 
• 54730-26-6 4-methoxymethoxy-3-(3,3-dimethylallyl)-2-hydroxyacetophenone 
• 151135-82-9 (E)-1-<2,4-dihydroxy-3-(3-methyl-2-butenyl)phenyl>-3-<4-hydroxy-3-(3-methyl-2-butenyl)phenyl>-2-propen-1-one 
• 54647-08-4 4-hydroxyderricin 

Relevant academic research and scientific papers

Synthesis and antibacterial activity of four natural chalcones and their derivatives

Four natural chalcones bearing hydroxyisoprenyl or prenyl groups, named Paratocarpin E (2), Xanthoangelol D (3), Angusticornin A (4) and Kanzonol C (5), were prepared by employing the Claisen-Schmidt condensation as the key step. In an attempt to investigate the effect of the hydroxyisoprenyl group on biological activity, two of their derivatives were also prepared for antibacterial activity research. The synthesized compounds were investigated for their expected antibacterial activities against Gram positive bacteria (Bacillus subtilis, Staphylococcus aureus) as well as Gram negative bacteria (Escherichia coli, Pseudomonas aeruginosa). Paratocarpin E (2) was found to be the most potent against two Gram positive bacteria while the majority of the remaining compounds showed promising activity as well. However, all of the compounds were inactive against both Gram-negative bacteria.

Synthesis method and use of natural product Paratocarpin E

The invention discloses a synthesis method and use of a natural product that is Paratocarpin E. The structure formula (I) of the natural product is shown in the description. The obtained isopentene chalcone type natural product Paratocarpin E has obvious

Synthesis method and use of natural product Angusticornin A

The invention discloses a synthesis method and use of a natural product that is Angusticornin A. The structure formula (I) of the natural product is shown in the description. The obtained natural product Angusticornin A has good inhibitory activity agains

Preparation method and application of natural product Xanthoangelol D and derivative thereof

The invention discloses a preparation method and application of an isopentenyl chalcone natural product and a derivative thereof. The structural general formula (I) and (II) of the isopentenyl chalcone natural product and the derivative thereof are as follows. Compared with a novel isopentenyl chalcone derivative, the obtained natural product Xanthoangelol D has inhibitory activity improved to a certain degree on bacillus subtilis. The preparation rout of the preparation method has fewer process steps, raw materials are easily available, and the preparation method is suitable for industrial production.

Synthetic method and application of natural product Kanzonol C and derivatives thereof

The invention discloses a synthetic method and application of a natural product Kanzonol C and derivatives thereof. The structural formula (I) and (II) are shown in the specification: compared with anatural product Kanzonol C, the obtained novel isopenten

Synthesis and antibacterial activity of chalcones bearing prenyl or geranyl groups from Angelica keiskei

Chalcones bearing prenyl or geranyl groups from Angelica keiskei, such as 4-hydroxyderricin (1a), xanthoangelol (1e), xanthoangelol F (1f), xanthoangelol H (2), deoxyxanthoangelol H (3), and deoxydihydroxanthoangelol H (4) and their derivatives were synthesized. From the evaluation of antibacterial activity of the synthesized chalcones, 1a, isobavachalcone (1b), 1e, 1f, bavachalcone (5a), and broussochalcone B (5b) were found to inhibit Gram-positive bacteria.