1546-95-8Relevant articles and documents
Syntheses and Reactions of Metal Organics. XVI. Synthesis and Hydrolysis of Dimethoxysilanediyl Bis(polyfluoroalkanoate)
Yoshino, Norio,Tominaga, Shin-ichi,Hirai, Hidefumi
, p. 2735 - 2738 (1991)
Four new silicon compounds, dimethoxysilanediyl bis(5H-octafluoropentanoate), (CH3O)2Si2, dimethoxysilanediyl bis(7H-dodecafluoroheptanoate), (CH3O)2Si2, dimethoxysilanediyl bis(9H-hexadecafluorononanoate, (CH3O)2Si2, and dimethoxysilanediyl bis(pentadecafluorooctanoate), (CH3O)2Si2, were prepared by the reaction of dichlorodimethoxysilane with sodium salts of fluoro-substituted carboxylic acid.The 1H NMR, 13C NMR, and 19F NMR and IR spectral data of these silicon compounds were obtained.In the course of a study of the s tability of the silicon compounds against hydrolysis by using 1H NMR spectral measurements, it was found that the ease of hydrolysis of the SiOCOR and the SiOCH3 moieties was exactly same.
Method for synthetizing dodecafluoroheptanoic acid through oxidization with potassium permanganate by phase transfer catalysis
-
Paragraph 0044-0054; 0056-0059, (2018/10/19)
The invention provides a method for synthetizing dodecafluoroheptanoic acid through oxidization with potassium permanganate by phase transfer catalysis. The method includes the following steps: 1) a step of an oxidation reaction, namely a step of adding the potassium permanganate, an organic weak acid solution and a quaternary ammonium salt catalyst into a reaction vessel, slowly dropping dodecafluoroheptanol into the reaction vessel, and continuously stirring to react for 0.5-1.5 h after the dropping is completed; and 2) a step of separation and purification, namely a step of carrying out vacuum filter on the reaction mixed liquor while hot by taking active carbon or diatomite as a filter aid, washing a filter cake by a sodium carbonate solution, combining a filtrate with a washing solution, adding an organic solvent to extract a aqueous solution after the acidification, and performing underpressure distillation, recrystallization and the like. According to the method provided by themethod, the dodecafluoroheptanoic acid is synthetized at 70 DEG C to 85 DEG C, the reaction conditions are mild, the post-treatment is simple, the time is about 2-4 h, the molar yield of the dodecafluoroheptanoic acid is 80%-90%, and the purity is no less than 97%. The dodecafluoroheptanoic acid can be used as a dispersing agent replacing perfluorocapylic acid in related industried.
METHODS OF PREPARING FLUORINATED CARBOXYLIC ACIDS AND THEIR SALTS
-
Page/Page column 36, (2011/05/06)
A method for preparing fluorinated carboxylic acids and theirs salts is described comprising subjecting a fluorinated alcohol of the general formula (A): A-CH2-OH to at least one first and at least one second oxidizing agent to produce a highly fluorinated carboxylic acid or their salts of the general formula (B): A-COO M+, wherein M+ represents a cation and wherein A in formulas (A) and (B) is the same and A represents the residue: Rf-[0]p-CX"Y"-[0]m-CX'Y'-[0]n-CXY- wherein Rf represents a fluorinated alkyl residue which may or may not contain one or more catenary oxygen atoms, p, m and n are independently from each other either 1 or O, X, X', X", Y, Y' and Y" are independently from each other H, F, CF3, or C2F5 with the proviso that not all of X, X', X", Y, Y' and Y' ' are H; or A represents the residue: R-CFX- wherein X and R are independently selected from a hydrogen, a halogen, or an alkyl, alkenyl, cycloalkyl, or aryl residue, which may or may not contain one or more fluorine atoms and which may or may not contain one or more catenary oxygen atoms; wherein said at least one first oxidizing agent is a compound that can be converted, by action of the second oxidizing agent, into a reactive species capable of oxidizing the fluorinated alcohol.
Practical preparation of some potentially anesthetic fluoroalkanes: regiocontrolled introduction of hydrogen atoms
Hudlicky, Tomas,Fan, Rulin,Reed, Josephine W.,Carver, David R.,Hudlicky, Milos,Eger, Edmond I.
, p. 9 - 14 (2007/10/02)
Methods are described for the large-scale preparation of a number of fluoroalkanes, which have been tested for general anesthesia.
