159878-29-2 Usage
General Description
The chemical compound "(3S,4aS,8aS)-N-tert-butyl-2-[(2R,3S)-2-hydroxy-3-{[N-(methylsulfonyl)-S-(naphthalen-2-yl)-D-cysteinyl]amino}-4-phenylbutyl]decahydroisoquinoline-3-carboxamide" is a complex organic compound classified as an isoquinoline carboxamide. It consists of a decahydroisoquinoline ring structure with a carboxamide group attached to it, as well as two side chains containing a tert-butyl group and a phenyl group. Additionally, it contains a hydroxy and a cysteinyl amino group, as well as a methylsulfonyl group. The compound is likely to have pharmaceutical properties, potentially serving as a ligand for certain receptors or enzymes due to the presence of functional groups such as hydroxy, amino, and carboxamide. Its structural complexity and diverse functional groups suggest that it may have multiple biological activities and potential applications in drug development and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 159878-29-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,9,8,7 and 8 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 159878-29:
(8*1)+(7*5)+(6*9)+(5*8)+(4*7)+(3*8)+(2*2)+(1*9)=202
202 % 10 = 2
So 159878-29-2 is a valid CAS Registry Number.
159878-29-2Relevant articles and documents
Reduction of peptide character of HIV protease inhibitors that exhibit nanomolar potency against multidrug resistant HIV-1 strains
Tamamura, Hirokazu,Koh, Yasuhiro,Ueda, Satoshi,Sasaki, Yoshikazu,Yamasaki, Tomonori,Aoki, Manabu,Maeda, Kenji,Watai, Yoriko,Arikuni, Hisashi,Otaka, Akira,Mitsuya, Hiroaki,Fujii, Nobutaka
, p. 1764 - 1768 (2007/10/03)
Novel HIV protease inhibitors containing a hydroxyethylamine dipeptide isostere as a transition state-mimic king structure were synthesized by combining substructures of known HIV protease inhibitors. Among them, TYA5 and TYB5 were proven to be not only p