16097-64-6 Usage
Description
2,4-dichloro-6-(trifluoromethyl)pyrimidine is an organic compound characterized by its pyrimidine ring structure, which features two chlorine atoms at the 2nd and 4th positions, and a trifluoromethyl group at the 6th position. 2,4-dichloro-6-(trifluoromethyl)pyrimidine is known for its potential applications in the synthesis of various chemical and pharmaceutical products due to its unique molecular structure and reactivity.
Uses
Used in Pharmaceutical Industry:
2,4-dichloro-6-(trifluoromethyl)pyrimidine is used as a synthetic intermediate for the development of 2,4-diaminopyrimidines derivatives. These derivatives exhibit antiplasmodial activities, making them valuable in the creation of new drugs to combat malaria and other related diseases. The compound's unique structure allows for the design of novel therapeutic agents with improved efficacy and reduced side effects.
Used in Chemical Synthesis:
In the field of organic chemistry, 2,4-dichloro-6-(trifluoromethyl)pyrimidine serves as a versatile building block for the synthesis of a wide range of chemical compounds. Its reactivity and functional groups enable chemists to create diverse molecules with various applications, such as agrochemicals, dyes, and other specialty chemicals. The compound's trifluoromethyl group, in particular, is known for its unique properties and can impart valuable characteristics to the synthesized products.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 24, p. 1243, 1987 DOI: 10.1002/jhet.5570240502
Check Digit Verification of cas no
The CAS Registry Mumber 16097-64-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,0,9 and 7 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 16097-64:
(7*1)+(6*6)+(5*0)+(4*9)+(3*7)+(2*6)+(1*4)=116
116 % 10 = 6
So 16097-64-6 is a valid CAS Registry Number.
InChI:InChI=1/C5HCl2F3N2/c6-3-1-2(5(8,9)10)11-4(7)12-3/h1H
16097-64-6Relevant articles and documents
HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF
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Page/Page column 154-155, (2022/02/22)
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; (I) wherein R1 R2, R4 and X1 are defeined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
N-(HETERO)ARYL-SUBSTITUTED HETEROYCLIC DERIVATIVES USEFUL FOR THE TREATMENT OF DISEASES OR CONDITIONS RELATED TO THE CENTRAL NERVOUS SYSTEM
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Page/Page column 51, (2016/04/20)
The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease, disorder or condition ameliorated by inhibition of a dopamine transporter); and methods of treating patients with such compounds; wherein R1, R2, R3, R4, R9a, R9b, R9c, R9d, R9e, R9f, m, n, A, L and B are as defined herein.
HEPATITIS B VIRAL ASSEMBLY EFFECTORS
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Paragraph 00122, (2015/05/05)
Novel assembly effector compounds having a therapeutic effect against hepatitis B viral (HBV) infection are disclosed. Assembly effector molecules described herein can lead to defective viral assembly and also may affect other viral activities associated with chronic HBV infection. Also disclosed is a process to synthesize disclosed compounds, method of treatment of HBV by administration of disclosed compounds, and use of these compounds in the manufacture of medicaments against HBV.