16837-08-4 Usage
General Description
6-Amino-1-methyl-2-thio-uracil is a chemical compound with the molecular formula C5H6N4S. It is a derivative of uracil, a naturally occurring compound found in RNA. This chemical is often used as a precursor in the synthesis of various medicinally important compounds, particularly antiviral agents. Its structure contains a thione group, which is known for its potential biological activities, making 6-Amino-1-methyl-2-thio-uracil a valuable starting material for the development of novel pharmaceuticals. Additionally, this compound has been studied for its potential anti-inflammatory and antioxidant properties, further expanding its potential applications in drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 16837-08-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,8,3 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 16837-08:
(7*1)+(6*6)+(5*8)+(4*3)+(3*7)+(2*0)+(1*8)=124
124 % 10 = 4
So 16837-08-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H7N3OS/c1-8-3(6)2-4(9)7-5(8)10/h2H,6H2,1H3,(H,7,9,10)
16837-08-4Relevant articles and documents
Synthesis and evaluation of antitumour activities of novel fused tri-And tetracyclic uracil derivatives
Elkalyoubi, Samar,Fayed, Eman
, p. 771 - 777 (2016)
Simple one-pot syntheses of indenopyrrolopyrimidines and indolopyrrolopyrimidines were achieved via the cyclocondensation of 6-Aminouracils and, respectively, ninhydrin and isatin in the presence of catalytic amounts of glacial acetic acid. Similarly, 5,6-diaminouracil derivatives were used as starting materials for the synthesis of indenopteridines and indolopteridines via their reaction with ninhydrin and isatin, respectively. The synthesised compounds were evaluated for antitumour activity against a human hepatocellular carcinoma cell line (HepG2), some showing antitumour activity comparable with 5-fluorouracil and imatinib.
