170697-87-7Relevant articles and documents
CAN-catalyzed vinylogous povarov reactions: The first three-component synthesis of 2-functionalized tetrahydroquinolines from anilines, cinnamaldehyde and vinyl ethers
Sridharan, Vellaisamy,Avenda?o, Carmen,Menéndez, J. Carlos
, p. 1079 - 1082 (2007)
The CAN-catalyzed reaction between anilines, cinnamaldehyde and vinyl ethers affords 2-styryl-1,2,3,4-tetrahydroquinolines. In the case of noncyclic vinyl ethers, these reactions are completely stereoselective and furnish exclusively the diastereomer with
High throughput one pot synthesis of 2-methylquinolines
Chandrashekarappa, Kiran Kumar H.,Mahadevan, Kittappa M.,Manjappa, Kiran B.
supporting information, p. 1368 - 1370 (2013/04/23)
Various 2-methylquinolines have been successfully synthesized by using anilines and ethyl vinyl ether in 1:3 mole ratios in the presence of acetic acid. Stirring at rt for 3-4 h followed by reflux for 3.5-4 h resulted in the corresponding 2-methylquinolines in good yield. Copyright
CAN-catalyzed three-component reaction between anilines and alkyl vinyl ethers: stereoselective synthesis of 2-methyl-1,2,3,4-tetrahydroquinolines and studies on their aromatization
Sridharan, Vellaisamy,Avenda?o, Carmen,Menéndez, J. Carlos
, p. 673 - 681 (2007/10/03)
The CAN-catalyzed reaction between anilines and vinyl ethers at room temperature provides a convenient and efficient access to?4-alkoxy-2-methyl-1,2,3,4-tetrahydroquinolines. This reaction is stereoselective, favouring a cis arrangement for the alkoxy and methyl groups, and involves a three-component process that leaves a molecule of alcohol as the only side product. 2-Methylquinoline derivatives were efficiently prepared from 4-alkoxy-2-methyl-1,2,3,4-tetrahydroquinolines by Pd-C-promoted dehydrogenation.
