178181-52-7Relevant articles and documents
Generating Monofluoro-Substituted Amines and Amino Acids by the Interaction of Inexpensive KF and Sulfamidates
Liang, Lu-Lu,Niu, Liang-Feng,Xu, Zhi-Hong,Yang, Lijun,Yao, Chuan,Zeng, Jun-Liang,Zou, Yu-Lu
, (2022/02/19)
The regioselective ring-opening of 1,2- and 1,3-sulfamidates with fluorine anion is reported. Direct construction of monofluoro-substituted amines and amino acid derivatives using inexpensive and easily available potassium fluoride (KF). The monofluorinat
ARYL, HETEROARY, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS
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Page/Page column 650, (2018/09/21)
Complement Factor D inhibitors, pharmaceutical compositions, and uses thereof, as well as processes for their manufacture are provided. The compounds provided include Formula I, Formula II, Formula III, Formula IV, and Formula V, or a pharmaceutically acceptable salt, prodrug, isotopic analog, N-oxide, or isolated isomer thereof, optionally in a pharmaceutically acceptable composition. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade.
C-terminal 18F-fluoroethylamidation exemplified on [Gly-OH9] oxytocin
Jelinski,Hamacher,Coenen
, p. 217 - 229 (2007/10/03)
The no-carrier-added (n.c.a.) 18F-fluoroethylamidation of the acid function of the protected nonapeptide Boc-Cys-Tyr(tBu)-Ile-Gln(Mtt)-Asn(Mtt)-Cys-Pro-Leu-Gly-OH forming the labelled peptide hormone derivative [Gly-(2-[18F]fluoroeth