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178488-37-4

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178488-37-4 Usage

General Description

Imidazo[1,2-a]pyridine-3-carboxaldehyde, 5-methyl- (9CI) is a chemical compound with the molecular formula C8H7N3O. It is a derivative of imidazo[1,2-a]pyridine and is commonly used in organic synthesis and medicinal chemistry as a building block for the synthesis of various pharmaceutical compounds. It is also used as a fluorescent probe in biological research and as a reagent for the detection and quantification of certain compounds. The compound has potential applications in drug discovery and development due to its unique structure and properties, making it an important chemical in various scientific and industrial fields.

Check Digit Verification of cas no

The CAS Registry Mumber 178488-37-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,8,4,8 and 8 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 178488-37:
(8*1)+(7*7)+(6*8)+(5*4)+(4*8)+(3*8)+(2*3)+(1*7)=194
194 % 10 = 4
So 178488-37-4 is a valid CAS Registry Number.

178488-37-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-methylimidazo[1,2-a]pyridine-3-carbaldehyde

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:178488-37-4 SDS

178488-37-4Relevant articles and documents

Microwave-assisted synthesis of 3-formyl substituted imidazo[1,2-a]pyridines

Kusy, Damian,Maniukiewicz, Waldemar,B?a?ewska, Katarzyna M.

supporting information, (2019/10/16)

An efficient, metal-free method for the synthesis of 3-formyl imidazo[1,2-a]pyridines is reported. The method utilises commercially available substrates and features a broad substrate scope. The intermediate enamine was isolated and a plausible reaction mechanism proposed.

Benzimidazolone as potent chymase inhibitor: Modulation of reactive metabolite formation in the hydrophobic (P1) region

Lo, Ho Yin,Nemoto, Peter A.,Kim, Jin Mi,Hao, Ming-Hong,Qian, Kevin C.,Farrow, Neil A.,Albaugh, Daniel R.,Fowler, Danielle M.,Schneiderman, Richard D.,Michael August,Martin, Leslie,Hill-Drzewi, Melissa,Pullen, Steven S.,Takahashi, Hidenori,De Lombaert, Stephane

scheme or table, p. 4533 - 4539 (2011/09/12)

A new class of chymase inhibitor featuring a benzimidazolone core with an acid side chain and a P1 hydrophobic moiety is described. Incubation of the lead compound with GSH resulted in the formation of a GSH conjugate on the benzothiophene P1 moiety. Replacement of the benzothiophene with different heterocyclic systems such as indoles and benzoisothiazole is feasible. Among the P1 replacements, benzoisothiazole prevents the formation of GSH conjugate and an in silico analysis of oxidative potentials agreed with the experimental outcome.

Reactions with N-chlorosuccinimide of various 5-methylimidazo[1,2-a]pyridine derivatives with an electron-withdrawing group substituted at the 3-position

Ikemoto, Tomomi,Wakimasu, Mitsuhiro

, p. 99 - 108 (2007/10/03)

Chlorination reactions using N-chlorosuccinimide (NCS) was investigated for various 5-methylimidazo[1,2-a]pyridine derivatives with an electron-withdrawing group substituted at the 3-position. These reactions showed different results, and by examining these, we proposed a reaction mechanism via the appropriate 3-halogenoimidazo[1,2-a]pyridium compounds as the reaction intermediates.

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