185427-48-9 Usage
Description
(E)-1-HEXENE-1,2-DIBORONIC ACID BIS(PINACOL) ESTER is a boron-containing chemical compound widely utilized in organic synthesis and as a reagent in various chemical reactions. It is known for its stability and versatility, making it a reliable component in the formation of carbon-carbon and carbon-heteroatom bonds. (E)-1-HEXENE-1,2-DIBORONIC ACID BIS(PINACOL) ESTER is particularly valuable in the preparation of pharmaceuticals and other organic molecules, as well as in the development of new synthetic methodologies for the production of complex organic molecules.
Uses
Used in Organic Synthesis:
(E)-1-HEXENE-1,2-DIBORONIC ACID BIS(PINACOL) ESTER is used as a reagent for the formation of carbon-carbon and carbon-heteroatom bonds, facilitating the synthesis of a wide range of organic molecules.
Used in Pharmaceutical Preparation:
In the pharmaceutical industry, (E)-1-HEXENE-1,2-DIBORONIC ACID BIS(PINACOL) ESTER is used as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Chemical Research:
(E)-1-HEXENE-1,2-DIBORONIC ACID BIS(PINACOL) ESTER is employed as a research tool in the field of organic chemistry, aiding in the exploration of new synthetic methodologies and the production of complex organic molecules.
Used in Material Science:
In material science, (E)-1-HEXENE-1,2-DIBORONIC ACID BIS(PINACOL) ESTER is used as a component in the development of new materials with specific properties, such as those with enhanced stability or reactivity.
Used in Chemical Process Development:
(E)-1-HEXENE-1,2-DIBORONIC ACID BIS(PINACOL) ESTER is utilized in the optimization and development of chemical processes, where its stability and reactivity are crucial for achieving desired outcomes in various industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 185427-48-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,5,4,2 and 7 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 185427-48:
(8*1)+(7*8)+(6*5)+(5*4)+(4*2)+(3*7)+(2*4)+(1*8)=159
159 % 10 = 9
So 185427-48-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H34B2O4/c1-10-11-12-14(20-23-17(6,7)18(8,9)24-20)13-19-21-15(2,3)16(4,5)22-19/h13H,10-12H2,1-9H3/b14-13-
185427-48-9Relevant articles and documents
Dehydrogenative Diboration of Alkynes Catalyzed by Ir/CO/tBuNC System
Lai, Qingheng,Ozerov, Oleg V.
, (2020/11/30)
Catalytic dehydrogenative diboration (DHDB) of alkyne with HBpin was achieved using [Ir(COD)Cl]2 and other related Ir precursors under CO atmosphere. The selectivity for DHDB over hydroboration was higher in less polar solvents and under higher
Synthesis of Polysubstituted Isoquinolines and Related Fused Pyridines from Alkenyl Boronic Esters via a Copper-Catalyzed Azidation/Aza-Wittig Condensation Sequence
Jayaram, Vankudoth,Sridhar, Tailor,Sharma, Gangavaram V. M.,Berrée, Fabienne,Carboni, Bertrand
, p. 843 - 853 (2018/01/28)
An efficient and straightforward synthesis of isoquinolines is reported from internal alkenyl boronic esters, easily prepared from the corresponding 1,2-bis(boronates), via a sequential copper-catalyzed azidation/aza-Wittig condensation. This synthetic method has been used to synthesize quinisocaine, a topical anesthetic used for the treatment of pain and pruritus, and further extended to thieno[2,3-c]pyridines by using 2-thiophenecarboxaldehyde as coupling partner in the first step.
Convenient synthesis of α,α-difluorinated carbonyl compounds from alkynes through a fluoro-deboronation process
Ramirez, Jesus,Fernandez, Elena
, p. 1698 - 1700 (2007/10/03)
Catalytic diboration of alkynes towards alkenyl diboronates provides suitable intermediates that can be converted into α-fluorinated and α,α-difluorinated carbonyl compounds via electrophilic fluorination with Selectfluor. Georg Thieme Verlag Stuttgart.