21541-97-9Relevant academic research and scientific papers
REACTION OF CONJUGATED NITRO OLEFINS WITH AROMATIC COMPOUNDS: A NEW ACYLMETHYLATION OF AROMATIC COMPOUNDS
Lee, Kilsung,Oh, Dong Young
, p. 2977 - 2978 (1988)
Reaction of conjugated nitro olefins with aromatic compounds, followed by hydrolytic treatment, gives acylmethylated aromatic compounds in good yield.
A synthesis of (E)-(1-organo-1-alkenyl)boronates by the palladium-catalyzed cross-coupling reaction of (E)-1,2-bis(boryl)-1-alkenes with organic halides: A formal carboboration of alkynes via the diboration-coupling sequence
Ishiyama, Tatsuo,Yamamoto, Masafumi,Miyaura, Norio
, p. 1117 - 1118 (1996)
(E)-1,2-Bis(boryl)-1-hexene, prepared by the platinum-catalyzed diboration of 1-hexyne with bis(pinacolato)diboron, regioselectively cross-coupled with aryl, 1-alkenyl, benzyl, and allyl halides in the presence of a palladium catalyst and a base to provide the corresponding pinacol esters of (E)-(1-butyl-1-alkenyl)boronic acid in good yields.
C-H Alkylation of Aldehydes by Merging TBADT Hydrogen Atom Transfer with Nickel Catalysis
Murugesan, Vetrivelan,Ganguly, Anirban,Karthika, Ardra,Rasappan, Ramesh
, p. 5389 - 5393 (2021/07/21)
Catalyst controlled site-selective C-H functionalization is a challenging but powerful tool in organic synthesis. Polarity-matched and sterically controlled hydrogen atom transfer (HAT) provides an excellent opportunity for site-selective functionalization. As such, the dual Ni/photoredox system was successfully employed to generate acyl radicals from aldehydes via selective formyl C-H activation and subsequently cross-coupled to generate ketones, a ubiquitous structural motif present in the vast majority of natural and bioactive molecules. However, only a handful of examples that are constrained to the use of aryl halides are developed. Given the wide availability of amines, we developed a cross-coupling reaction via C-N bond cleavage using the economic nickel and TBADT catalyst for the first time. A range of alkyl and aryl aldehydes were cross-coupled with benzylic and allylic pyridinium salts to afford ketones with a broad spectrum of functional group tolerance. High regioselectivity toward formyl C-H bonds even in the presence of α-methylene carbonyl or α-amino/oxy methylene was obtained.
Palladium-catalyzed intermolecular hydroamination of alkynes: A dramatic rate-enhancement effect of o-aminophenol
Shimada, Tomohiro,Yamamoto, Yoshinori
, p. 12670 - 12671 (2007/10/05)
The hydroamination of alkynes using o-aminophenol proceeds in very high to good yields in the presence of Pd(NO3)2 catalyst. Remarkable rate enhancement with o-aminophenol is presumably due to the chelation effect of the ortho OH group to palladium. Copyright
