19652-13-2 Usage
Uses
5-Amino-3-(4-methoxyphenyl)-1-phenylpyrazole (3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-5-amine) may be used in the preparation of pyrazolo[3,4-b]pyridines derivatives with potent anti-inflammatory activity against interleukin-6 (IL-6).
General Description
5-Amino-3-(4-methoxyphenyl)-1-phenylpyrazole belongs to a family of 5-aminopyrazole derivatives, which are bioactive agents. They find a wide range of applications in the pharmaceutical and agrochemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 19652-13-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,6,5 and 2 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 19652-13:
(7*1)+(6*9)+(5*6)+(4*5)+(3*2)+(2*1)+(1*3)=122
122 % 10 = 2
So 19652-13-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H15N3O/c1-20-14-9-7-12(8-10-14)15-11-16(17)19(18-15)13-5-3-2-4-6-13/h2-11H,17H2,1H3
19652-13-2Relevant articles and documents
Synthesis of novel twisted heterocyclic analogues of s-indacenes
Danel, Krzysztof S.,Uchacz, Tomasz,Karelus, Marcin
, p. 272 - 280 (2011/08/21)
A series of novel compounds as candidates for OLED applications were synthesized by cyclization reactions of neighbouring rings in dipyrazolo[3,4-b:4',3'-e]pyridines 8-12. The desymmetrization of these molecules leading to 14 can be performed using both KOH/isoquinoline or palladium catalysts. The resulting structures contain a helical arrangement of four different rings. ARKAT-USA, Inc.
Synthesis of some novel fluorinated pyrazolo[3,4-b]pyridines
Singh,Naithani, Rajesh,Aggarwal, Ranjana,Prakash, Om
, p. 4359 - 4367 (2007/10/03)
Reaction of 5-amino-3-substituted pyrazoles (1a-c) and 5-amino-1,3- disubstituted pyrazoles (1d-i) with fluorinated-β-diketones (2) results in the formation of the single isomer of pyrazolo[3,4-b]pyridines (4a-h). A one-pot procedure for the synthesis of
