197020-60-3 Usage
Molecular Structure
The compound has an aziridine ring with a carboxyl group, a 2-methyl group, and a 1,1-dimethylethyl ester group.
Stereochemistry
The compound has a specific (2S) stereochemical configuration, which is important for its applications in chiral drugs and organic synthesis.
Reactivity
The compound is highly reactive, which makes it useful as an intermediate in the synthesis of various pharmaceuticals and agrochemicals.
Versatility
The compound has a wide range of applications, including the production of polymers, resins, and as a reagent in chemical reactions.
Toxicity
The compound is toxic and potentially hazardous, which requires strict regulation and control of its production and use.
Usage
Commonly used in the pharmaceutical and chemical industries as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, as well as in the production of polymers, resins, and as a reagent in chemical reactions.
Chirality
The (2S) enantiomer of the compound has a specific stereochemical configuration, which is useful in the production of chiral drugs and as a chiral building block in organic synthesis.
Regulation
The compound is regulated and strictly controlled due to its toxic and potentially hazardous nature.
Check Digit Verification of cas no
The CAS Registry Mumber 197020-60-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,7,0,2 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 197020-60:
(8*1)+(7*9)+(6*7)+(5*0)+(4*2)+(3*0)+(2*6)+(1*0)=133
133 % 10 = 3
So 197020-60-3 is a valid CAS Registry Number.
197020-60-3Relevant articles and documents
An improved process for the N-alkylation of indoles using chiral N-protected 2-methylaziridines
Giles, Paul R.,Rogers-Evans, Mark,Soukup, Milan,Knight, John
, p. 22 - 24 (2003)
An improved process for the N-alkylation of indoles using N-protected homochiral aziridines has been developed. This procedure allows reduced quantities of homochiral starting material to be used and leads to improved overall yields and operability.
Aziridine-2-carboxaldehyde dimers undergo homo-Ugi 4-component-5-center reactions
Rotstein, Benjamin H.,Yudin, Andrei K.
, p. 2851 - 2858 (2012/11/07)
Dimeric α-aziridine aldehydes have been used as the aldehyde component in Ugi and Passerini reactions. The highly reactive mixed anhydride intermediate is subject to nucleophilic attack by the aziridine, leading to homo-Ugi' β-acylaziridinyl-α-aminoamides. The products can be readily transformed into substituted lactones. Georg Thieme Verlag Stuttgart ? New York.
Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists
-
Page/Page column 27, (2010/11/08)
The present invention provides serotonergic aminoalkylbenzofurans of Formula (I): where R, R1, R2, R3, R4, R4′, R5, R5′, and R12 are as described in the specification.
