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19948-27-7

19948-27-7

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19948-27-7 Usage

General Description

1-Methyl-3-hydroxysuccinimide is a chemical compound used in organic synthesis and pharmaceutical research. It is a derivative of succinimide with a methyl group and a hydroxyl group attached to the carbon atoms. This chemical is commonly used as a reagent in the synthesis of various bioactive molecules and pharmaceutical intermediates. Its unique structure and reactivity make it valuable for the modification of proteins and peptides, as well as for the preparation of drug conjugates and prodrugs. Additionally, 1-methyl-3-hydroxysuccinimide is also used as a coupling agent in the production of protein conjugates for use in antibody-drug conjugates and other targeted drug delivery systems. It is important to handle this compound with caution and in accordance with safety protocols due to its potential hazards.

Check Digit Verification of cas no

The CAS Registry Mumber 19948-27-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,9,4 and 8 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 19948-27:
(7*1)+(6*9)+(5*9)+(4*4)+(3*8)+(2*2)+(1*7)=157
157 % 10 = 7
So 19948-27-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H7NO3/c1-6-4(8)2-3(7)5(6)9/h3,7H,2H2,1H3

19948-27-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-METHYL-3-HYDROXYSUCCINIMIDE

1.2 Other means of identification

Product number -
Other names 3-hydroxy-1-methylpyrrolidin-2,5-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19948-27-7 SDS

19948-27-7Downstream Products

19948-27-7Relevant articles and documents

Preparation method of 1-methyl-3-pyrrolidinol

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Paragraph 0051; 0056-0058; 0064; 0069-0071; 0077; 0082;..., (2021/09/01)

The invention relates to the technical field of synthesis of medical intermediates, and particularly discloses a preparation method of 1-methyl-3-pyrrolidinol. The preparation method comprises the following steps that S1, a compound I and a compound II are subjected to a ring closing reaction, so a compound III is obtained; and S2, the compound III obtained in the step S1 and a reducing agent IV are subjected to a reduction reaction, so 1-methyl-3-pyrrolidinol is obtained, wherein the compound I, the compound II and the compound III are as shown in the specification; and the reducing agent IV is one or more selected from a group consisting of sodium borohydride, potassium borohydride, boron trifluoride-diethyl ether and boron tribromide-diethyl ether. According to the preparation method, the compound II and the compound I are selected and subjected to the ring closing reaction to obtain the intermediate compound III, and the compound III is solid and is easy to crystallize and purify, so the purification difficulty of the intermediate is reduced, the purity of the intermediate is favorably improved, and the product quality of the 1-methyl-3-pyrrolidinol is further improved.

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