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1000370-76-2

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1000370-76-2 Usage

General Description

"(R)-3-(2-Nitro-phenylamino)-pyrrolidine-1-carboxylic acid tert-butyl ester" is a chemical compound that belongs to the class of pyrrolidine derivatives. It is often used as an intermediate in the synthesis of pharmaceutical compounds and as a building block in organic synthesis. The compound is commonly used in medicinal chemistry research for the development of new drugs, particularly in the area of cardiovascular and metabolic diseases. Additionally, it has been studied for its potential anti-inflammatory and anticancer properties. The tert-butyl ester moiety in the compound can enhance its stability and pharmacokinetic properties, making it a valuable tool in drug discovery and development.

Check Digit Verification of cas no

The CAS Registry Mumber 1000370-76-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,3,7 and 0 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1000370-76:
(9*1)+(8*0)+(7*0)+(6*0)+(5*3)+(4*7)+(3*0)+(2*7)+(1*6)=72
72 % 10 = 2
So 1000370-76-2 is a valid CAS Registry Number.

1000370-76-2Downstream Products

1000370-76-2Relevant articles and documents

New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation

Frohn, Mike,Xu, Han,Zou, Xiaoming,Chang, Catherine,McElvaine, Michele,Plant, Matthew H.,Wong, Min,Tagari, Philip,Hungate, Randall,Buerli, Roland W.

, p. 6633 - 6637 (2007)

We report the development of the novel N-substituted benzimidazole 11 as a potent and selective human formyl peptide receptor-like 1 (hFPRL1) agonist. This compound and its less active enantiomer 12 were identified as useful tools for studying receptor function in vitro.

1-CYANO-PYRROLIDINE DERIVATIVES AS INHIBITORS OF USP30.

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Page/Page column 71, (2018/02/03)

The present invention relates to novel compounds and methods for the manufacture of inhibitors of deubiquitylatingenzymes (DUBs). In particular, the invention relates to the inhibition of ubiquitin C- terminal hydrolase 30 or Ubiquitin Specific Peptidase 30 (USP30). The invention further relates to the use of DUB inhibitors in the treatment of conditions involving mitochondrial dysfunction and cancer. Compounds of the invention include compounds having the formula (I) (I) or a pharmaceutically acceptable salt thereof, wherein R1, R 2, R 3, m, L and X are as defined herein.

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