100046-79-5Relevant academic research and scientific papers
Studies on butenolides: 2-Arylidene-4-(substituted aryl)but- 3-en-4-olides - Synthesis, reactions and biological activity
Khan,Husain,Sharma
, p. 2160 - 2171 (2007/10/03)
2-Arylidene-4-(substituted aryl)but-3-en-4-olides also known as 3 -arylidene-5-(substituted aryl)-2(3H)-furanones have been prepared from 3-(substituted aroyl) propionic acid and aromatic aldehydes. Some of the selected butenolides have been reacted with ammonia and benzylamine to give corresponding pyrrolones and N-benzylpyrrolones respectively and characterized on the basis of 1H NMR and Mass spectrometric data and elemental analysis results. These compounds have been tested for anti-inflammatory and antimicrobial actions.
Synthesis of Enol Lactones of 3-Aroyl-2-(thienylmethylene)-propionic Acids and their Conversion into the Corresponding 4-Arylbenzothiophene-6-carboxylic Acids
Guirguis, Nadia R.,Awad, Boshra M.,Saad, Hanaa A.
, p. 1003 - 1011 (2007/10/02)
Heterocyclic aldehydes such as 2-thiophenecarbaldehyde (1) condense with 3-aroylpropionic acids 2 or their sodium salts to give the enol lactones 3a-d of 3-aroyl-2-(2-thienylmethylene)propionic acids.Isomerization of 3a-d leads to the corresponding 4-aryl
