100063-06-7

Basic information

• Product Name: 2-HYDROXY-2-PHENYL-1-(1H-PYRROL-2-YL)ETHANONE
• Synonyms: 2-HYDROXY-2-PHENYL-1-(1H-PYRROL-2-YL)ETHANONE
• CAS NO: 100063-06-7
• Molecular Formula: C₁₂H₁₁NO₂
• Molecular Weight: 201.22
• Mol File: 100063-06-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-HYDROXY-2-PHENYL-1-(1H-PYRROL-2-YL)ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXY-2-PHENYL-1-(1H-PYRROL-2-YL)ETHANONE(100063-06-7)
• EPA Substance Registry System: 2-HYDROXY-2-PHENYL-1-(1H-PYRROL-2-YL)ETHANONE(100063-06-7)

Safety Data

• Hazardous Substances Data: 100063-06-7(Hazardous Substances Data)

Upstream product

• 1003-29-8 2-pyrrole aldehyde 
• 100-52-7 benzaldehyde 

Downstream Products

• 1260146-44-8 1-phenyl-2-(1H-pyrrol-2-yl)ethanol 
• 110461-20-6 1-phenyl-2-(1H-pyrrol-2-yl)ethane-1,2-dione 
• 1260146-60-8 2-hydroxy-2-phenyl-1-(1H-pyrrol-2-yl)ethanone 
• 107413-95-6 2-(3-dimethylamino-propoxy)-2-phenyl-1-pyrrol-2-yl-ethanone 
• 100710-74-5 2-methoxy-1-(1-methyl-pyrrol-2-yl)-2-phenyl-ethanone 

Relevant articles and documents

Enantioselective aerobic oxidation of α-hydroxy-ketones catalyzed by oxidovanadium(V) methoxides bearing chiral, N-salicylidene- tert -butylglycinates

Chiral oxidovanadium(V) methoxides prepared from 3,5-disubstituted-N- salicylidene-l-tert-butylglycines and vanadyl sulfate in air-saturated MeOH serve as highly enantioselective catalysts for asymmetric aerobic oxidations and kinetic resolution of alkyl, aryl, and heteroaryl α-hydroxy-ketones with differed α-substituents at ambient temperature in toluene or TBME (tert-butyl methyl ether). The best scenarios involve the use of complexes which bear the tridendate templates derived from 3,5-diphenyl- or 3-o-biphenyl-5-nitro-salicyaldehyde. The kinetic resolution selectivities of the aerobic oxidation process are in the range of 12 to >1000 based on the selectivity factors (krel).