1000866-32-9Relevant academic research and scientific papers
An efficient stereoselective total synthesis of 11β-methoxycurvularin
Yadav,Vani, C. Divya,Bhasker,Reddy, B.V. Subba
, p. 291 - 300 (2014/10/15)
A very short and efficient stereoselective total synthesis of a macrocyclic ketone, 11β-methoxycurvularin was achieved by employing the Sharpless asymmetric epoxidation, formation of propargyl alcohols from an epoxy-chloride, and intramolecular Friedel-Cr
Stereoselective syntheses of 11-α-methoxycurvularin and 11-β-methoxycurvularin
Venkateswar Reddy,Sateesh Chandra Kumar,Suresh Babu,Madhusudana Rao
scheme or table, p. 4117 - 4120 (2009/12/01)
A stereoselective synthesis of potent cytotoxic macrolides, 11-α-methoxycurvularin and 11-β-methoxycurvularin has been accomplished. The synthesis entailed Maruoka asymmetric allylation to introduce the stereocentres at C-11 and the key fragment was insta
First total syntheses and spectral data corrections of 11-α- methoxycurvularin and 11-β-methoxycurvularin
Liang, Qiren,Sun, Yongquan,Yu, Binxun,She, Xuegong,Pan, Xinfu
, p. 9846 - 9849 (2008/09/16)
(Chemical Equation Presented) Concise and efficient total syntheses of 11-α-methoxycurvularin and 11-β-methoxycurvularin were accomplished for the first time. The three-component linchpin coupling and intramolecular acylation reactions were key steps, in which we found the spectral data of 11-α-methoxycurvularin and 11-β-methoxycurvularin, reported in the literature, were reversed with each other.
