1001022-93-0Relevant articles and documents
Highly enantioselective thiourea-catalyzed nitro-mannich reactions
Yoon, Tehshik P.,Jacobsen, Eric N.
, p. 466 - 468 (2005)
(Chemical Equation Presented) Approaching "privileged" status? A new and highly effective enantioselective catalyst for the nitro-Mannich reaction was identified by modification of thioureabased Strecker catalysts (see scheme). Products are obtained in hi
Catalytic enantioselective aza-Henry reaction with broad substrate scope
Palomo, Claudio,Oiarbide, Mikel,Laso, Antonio,Lopez, Rosa
, p. 17622 - 17623 (2005)
In situ generated azomethines from readily available precursors react with nitromethane in the presence of 120 mol % of CsOH·H2O and 12 mol % of quinine- and cinchonidine-derived quaternary ammonium chlorides to provide the corresponding aza-He
Biodegradable Chitosan-Derived Thioureas as Recoverable Supported Organocatalysts – Application to the Stereoselective Aza-Henry Reaction
Andrés, José M.,González, Fernando,Maestro, Alicia,Pedrosa, Rafael,Valle, María
, p. 3658 - 3665 (2017/07/22)
Eight different biodegradable chitosan-supported bifunctional chiral thioureas have been prepared as a greener and more sustainable alternative to those supported on petrochemical-derived polymers. These organocatalysts promoted an enantioselective aza-He
Organocatalytic Enantioselective Transfer Hydrogenation of β-Amino Nitroolefins
Ferraro, Antonino,Bernardi, Luca,Fochi, Mariafrancesca
, p. 1561 - 1565 (2016/10/13)
The asymmetric organocatalytic transfer hydrogenation of β-acylamino and β-tert-butyloxycarbonylamino nitroolefins has been successfully realised in excellent enantioselectivities and yields (up to >99% ee, 97% yield) with a simple thiourea catalyst and a Hantzsch ester as hydrogen source, giving a direct access to enantiomerically pure β-amino nitroalkanes. (Figure presented.).
