1001322-87-7

Usage

Uses

Used in Organic Synthesis:
8-bromo-7-fluoro-2-methoxyquinoline is used as a key intermediate in the synthesis of complex organic molecules for various applications, including pharmaceuticals, agrochemicals, and materials science. Its unique structural features allow for versatile chemical reactions and modifications, facilitating the creation of novel compounds with desired properties.
Used in Research Laboratories:
In research settings, 8-bromo-7-fluoro-2-methoxyquinoline serves as a valuable compound for studying the effects of different substituents on the quinoline core. It aids in understanding the structure-activity relationships and exploring the potential applications of quinoline-based compounds in various fields.
Used in Pharmaceutical Industry:
8-bromo-7-fluoro-2-methoxyquinoline is used as a building block in the development of new pharmaceutical agents. Its unique chemical structure can be exploited to design drugs with improved potency, selectivity, and reduced side effects. 8-bromo-7-fluoro-2-methoxyquinoline can be further modified to target specific biological pathways or receptors, leading to the discovery of innovative therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 8-bromo-7-fluoro-2-methoxyquinoline can be employed as a precursor for the synthesis of novel pesticides or herbicides. Its unique properties may contribute to the development of more effective and environmentally friendly agrochemicals.
Used in Materials Science:
8-bromo-7-fluoro-2-methoxyquinoline can also be utilized in the field of materials science for the development of new materials with specific properties. Its incorporation into polymers, for instance, may lead to materials with improved thermal stability, electrical conductivity, or other desirable characteristics.
Overall, 8-bromo-7-fluoro-2-methoxyquinoline is a versatile compound with a wide range of applications across various industries, primarily due to its unique structural features and the potential for further chemical modifications.

Upstream product

• 1001322-86-6 8-bromo-7-fluoroquinolin-2(1H)-one 
• 74-88-4 methyl iodide 
• 1001322-85-5 N-(2-bromo-3-fluorophenyl)cinnamamide 
• 111721-75-6 2-bromo-3-fluoroaniline 
• 1152781-66-2 8-bromo-2-chloro-7-fluoroquinoline 
• 124-41-4 sodium methylate 

Downstream Products

• 1075260-05-7 phenylmethyl [((3S,4S)-1-{[(3R)-10-fluoro-5-oxo-2,3-dihydro-5H-[1,4]oxazino[2,3,4-ij]quinolin-3-yl]methyl}-4-hydroxy-3-pyrrolidinyl)methyl]carbamate 
• 1075260-71-7 (S)-3-({4-[(6,7-dihydro[1,4]dioxino[2,3-c]pyridazin-3-ylmethyl)amino]-1-piperidinyl}methyl)-10-fluoro-2,3-dihydro-1H,5H-pyrido[3,2,1-ij]quinolin-5-one benzoate 
• 1075702-28-1 (R)-3-({4-[(6,7-dihydro[1,4]dioxino[2,3-c]pyridazin-3-ylmethyl)amino]-1-piperidinyl}methyl)-10-fluoro-2,3-dihydro-1H,5H-pyrido[3,2,1-ij]quinolin-5-one benzoate 

Relevant academic research and scientific papers

Optimization of TopoIV Potency, ADMET Properties, and hERG Inhibition of 5-Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with in Vivo Efficacy against MRSA

Novel bacterial topoisomerase inhibitors (NBTIs) are among the most promising new antibiotics in preclinical/clinical development. We previously reported dioxane-linked NBTIs with potent antistaphylococcal activity and reduced hERG inhibition, a key safet

TRICYCLIC NITROGEN CONTAINING HETEROCYCLES AS ANTIBACTERIAL AGENTS

Tricyclic nitrogen containing compounds and their use as antibacterials.

SUBSTITUTED 1-METHYL-1H-QUINOLIN-2-ONES AND 1-METHYL-1H-1,5-NAPHTHYRIDIN-2-ONES AS ANTIBACTERIALS

Bicyclic nitrogen containing compounds of formula (I) and their use as antibacterials.

AZATRICYCLIC COMPOUNDS AND THEIR USE

Tricyclic nitrogen containing compounds),of formula (I) or a pharmaceutically, acceptable salt, solvate and/or N-oxide thereof: and their use as antibacterials.

Pyrrolo[3,2,1-ij]quinoline-4-one derivatives for treating tuberculosis

Tricyclic nitrogen-containing compounds of Formula (I) and pharmaceutically acceptable derivatives thereof: compositions containing them, their use in the treatment of tuberculosis, and methods for the preparation of such compounds.