1001346-91-3

Basic information

• Product Name: 4-Amino-2-fluoro-5-methoxybenzoic acid
• Synonyms: 4-Amino-2-fluoro-5-methoxybenzoic acid
• CAS NO: 1001346-91-3
• Molecular Formula: C₈H₈FNO₃
• Molecular Weight: 185.1524232
• Mol File: 1001346-91-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 368.924 °C at 760 mmHg
• Flash Point: 176.919 °C
• Appearance: /
• Density: 1.398 g/cm³
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 4-Amino-2-fluoro-5-methoxybenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-2-fluoro-5-methoxybenzoic acid(1001346-91-3)
• EPA Substance Registry System: 4-Amino-2-fluoro-5-methoxybenzoic acid(1001346-91-3)

Safety Data

• Hazardous Substances Data: 1001346-91-3(Hazardous Substances Data)

Usage

General Description

4-Amino-2-fluoro-5-methoxybenzoic acid is a chemical compound with the molecular formula C8H8FNO4. It is a derivative of benzoic acid that contains an amino group, a fluorine atom, and a methoxy group. 4-Amino-2-fluoro-5-methoxybenzoic acid is often used as an intermediate or building block in the synthesis of pharmaceuticals and other organic compounds. Its properties and uses make it important in the fields of medicinal chemistry and drug development. Additionally, it has the potential to exhibit biological activity and may be studied for its potential pharmacological effects.

InChI:InChI=1S/C8H8FNO3/c1-13-7-2-4(8(11)12)5(9)3-6(7)10/h2-3H,10H2,1H3,(H,11,12)

Upstream product

• 1001345-80-7 2‐fluoro‐5‐methoxy‐4‐nitrobenzoic acid 
• 116465-48-6 2,5‐difluoro‐4‐nitrobenzoic acid 
• 924868-81-5 methyl 2,5-difluoro-4-nitrobenzoate 

Downstream Products

• 1137869-87-4 methyl 4-amino-2-fluoro-5-methoxybenzoate 
• 1137868-56-4 9-cyclopentyl-7,7-difluoro-2-(5-fluoro-2-methoxyphenylamino)-5-methyl-8,9-dihydro-5H-pyrimido[4,5-b][1,4]diazepin-6(7H)-one 
• 1137867-66-3 4-(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-ylamino)-2-fluoro-5-methoxy-benzoic acid 
• 1214265-72-1 (R)-4-(5-cyclopentyl-7-(ethoxycarbonyl)-6-ethyl-5,6-dihydroimidazo[1,5-f]pteridin-3-ylamino)-2-fluoro-5-methoxybenzoic acid 
• 1214265-77-6 (R)-4-(7-cyano-5-cyclopentyl-6-ethyl-5,6-dihydroimidazo[1,5-f]pteridin-3-ylamino)-2-fluoro-5-methoxybenzoic acid 
• 1214265-80-1 (R)-4-(7-cyano-6-ethyl-5-isopropyl-5,6-dihydroimidazo[1,5-f]pteridin-3-ylamino)-2-fluoro-5-methoxybenzoic acid 
• 1401423-22-0 (4-(4-(cyclopropylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)-2-fluoro-5-methoxyphenyl)(morpholino)methanone 
• 1362692-50-9 (4-amino-2-fluoro-5-methoxyphenyl)(morpholino)-methanone 
• 1401423-27-5 4-(4-ethylamino-5-(trifluoromethyl)pyrimidin-2-ylamino)-2-fluoro-N-(2-hydroxy-2-methyl-propyl)-5-methoxy-benzamide 

Relevant articles and documents

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POLO-LIKE KINASE INHIBITORS

Compounds of the following formula are provided for use with kinases: (I) wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates use

NOVEL COMPOUNDS

There is provided a compound of formula (I): processes for the manufacture thereof, pharmaceutical compositions thereof and uses in therapy.