1001407-06-2

Upstream product

• 34245-85-7 3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-α-D-glucopyranosyl bromide 
• 1001407-03-9 4-nitrophenyl 3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-β-D-glucopyranoside 
• 1001407-04-0 4-aminophenyl 3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-β-D-glucopyranoside 
• 100-02-7 4-nitro-phenol 
• 1001407-08-4 N-[4-(3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-β-D-glucopyranosyloxy)phenyl]-2-aminoacetamide 
• 305-03-3 chlorambucil 
• 1001407-07-3 N-[4-(3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-β-D-glucopyranosyloxy)phenyl]-2-(benzyloxycarbonylamino)acetamide 

Relevant academic research and scientific papers

Synthesis and cytotoxic properties of new fluorodeoxyglucose-coupled chlorambucil derivatives

Frequently used in the treatment of malignant cells, alkylating agents, like most anticancer substances, produce adverse side effects caused by the toxicity of the agents toward normal tissues and lose efficiency through poor distribution to target sites.

Conjugates of 2-fluoro-2-deoxy-glucose and their uses as anti cancer agents

The present invention relates to compounds of general formula (I): wherein: - R1, R2 and R3 mean, independently from the others, an hydrogen atom or an optionally substituted lower alkyl, a (C1-C7)acy