100192-15-2Relevant academic research and scientific papers
Useful four-carbon synthons en route to monastrol analogs
Abdou, Amr M.,Botros,Hassan, Rasha A.,Kamel, Mona M.,Taber, Douglass F.,Taher, Azza T.
, p. 139 - 146 (2015/02/18)
A simple protocol has been established for the preparation of a family of crystalline N-aryl γ-hydroxycrotonamides, useful four-carbon synthons. These were further elaborated to analogs of monastrol having variant ester sidechains, that were evaluated for their anticancer activity employing the NCI 60 cell line panel.
