10021-67-7

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 32, p. 1255, 1967 DOI: 10.1021/jo01279a100

InChI:InChI=1/C6H9NOS/c7-4-5(8)6-2-1-3-9-6/h1-3,5,8H,4,7H2

Upstream product

• 313276-47-0 2-amminometil-2-tienilchetone 
• 7732-18-5 water 
• 139224-74-1 2-(thiophen-2-yl)-2-((trimethylsilyl)oxy)acetonitrile 
• 78539-78-3 2-azido-1-(thiophen-2-yl)ethanol 
• 473552-25-9 (R)-(+)-2-azido-1-(2'-thienyl)ethanol 
• 70996-65-5 N-[(thien-2-ylcarbonyl)methyl]amine hydrochloride 
• 357952-93-3 (R)-(+)-1-(2-Thienyl)-2-(p-tolylsulfonyloxy)ethanol 

Downstream Products

• 76175-43-4 6-(2-tienil)-4-benzilmorfolin-3-one 
• 76175-41-2 2-(benzylamino)-1-(thien-2-yl)ethanol 

Relevant academic research and scientific papers

A facile synthesis of (R)-(-)-2-azido-1-arylethanols from 2-azido-1-arylketones using baker's yeast

A novel and efficient stereoselective reduction of 2-azido-1-aryl ketones using baker's yeast is described.

Application of optically active 1,2-diol monotosylates for synthesis of β-azido and β-amino alcohols with very high enantiomeric purity. Synthesis of enantiopure (R)-octopamine, (R)-tembamide and (R)-aegeline

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Hypocholesterolemic agents

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Aminoalcohols II: Preparation of Enantiomerically Pure Pharmacologically Active β-Aminoalcohols

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2-(2-Thienyl)morpholines with CNS activity

The synthesis and pharmacological investigation of 2-(2-thienyl)morpholine and some of its derivatives substituted on the nitrogen are described. The non-substituted compound showed interesting antidepressive properties with a pharmacological profile similar to that of imipramine.