100230-78-2

Basic information

• Product Name: (2S)-N-(3-methyl-2-nitrobenzoyl)proline
• CAS NO: 100230-78-2
• Molecular Weight: 278.265
• Mol File: 100230-78-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S)-N-(3-methyl-2-nitrobenzoyl)proline(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-N-(3-methyl-2-nitrobenzoyl)proline(100230-78-2)
• EPA Substance Registry System: (2S)-N-(3-methyl-2-nitrobenzoyl)proline(100230-78-2)

Safety Data

• Hazardous Substances Data: 100230-78-2(Hazardous Substances Data)

Upstream product

• 5437-38-7 3-methyl-2-nitrobenzoic acid 
• 50424-93-6 3-methyl-2-nitrobenzoyl chloride 
• 147-85-3 L-proline 

Downstream Products

• 100230-99-7 (S)-1-(3-Methyl-2-nitro-benzoyl)-pyrrolidine-2-carbonyl chloride 
• 175409-50-4 (S)-1-(3-Methyl-2-nitro-benzoyl)-pyrrolidine-2-carboxylic acid methyl ester 
• 176387-48-7 (S)-1-(3-Methyl-2-nitro-thiobenzoyl)-pyrrolidine-2-carbothioaldehyde 
• 175521-33-2 (S)-1-(3-Methyl-2-nitro-benzoyl)-pyrrolidine-2-carbaldehyde 
• 100243-62-7 N-(3-methyl-2-nitrobenzoyl)pyrrolidine-2-carboxaldehyde 

Relevant articles and documents

A new facile procedure for the preparation of pyrrolo[2,1-c][1,4]benzodiazepines : Synthesis of the antibiotic DC-81 and its thio analogue

An efficient synthesis of the imine form of the pyrrolo[2,1-c][1,4] benzodiazepine ring system based on a new reductive cyclization procedure is described. The naturally occuring antibiotic DC-81(5c) and its 5-thio analogue (7c) have also been synthesized to illustrate the usefulness of this methodology.