100238-55-9

Basic information

• Product Name: 4-(2-CHLOROETHOXY)PHENOL
• Synonyms: 4-(2-CHLOROETHOXY)PHENOL;4-(2-chloroethoxy)-
• CAS NO: 100238-55-9
• Molecular Formula: C₈H₉ClO₂
• Molecular Weight: 172.61
• Product Categories: API intermediates
• Mol File: 100238-55-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 301.819°C at 760 mmHg
• Flash Point: 136.335°C
• Appearance: /
• Density: 1.235g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.547
• CAS DataBase Reference: 4-(2-CHLOROETHOXY)PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-CHLOROETHOXY)PHENOL(100238-55-9)
• EPA Substance Registry System: 4-(2-CHLOROETHOXY)PHENOL(100238-55-9)

Safety Data

• Hazardous Substances Data: 100238-55-9(Hazardous Substances Data)

Usage

General Description

4-(2-chloroethoxy)phenol, also known as cephaeline, is a synthetic chemical compound with the molecular formula C8H9ClO2. It is a phenolic compound that contains a chlorine atom and an ethoxy group attached to a phenol ring. This chemical is commonly used in the production of various pharmaceuticals and agrochemicals due to its antimicrobial and antibacterial properties. It is also used as an intermediate in the synthesis of other organic compounds. 4-(2-chloroethoxy)phenol is a colorless to light yellow liquid with a slightly phenolic odor, and it is important to handle it with proper safety precautions as it can irritate the skin, eyes, and respiratory system if not handled properly.

InChI:InChI=1/C8H9ClO2/c9-5-6-11-8-3-1-7(10)2-4-8/h1-4,10H,5-6H2

Upstream product

• 107-04-0 1-Bromo-2-chloroethane 
• 123-31-9 hydroquinone 
• 3383-74-2 1-(2-chloroethoxy)-4-methoxybenzene 
• 54373-15-8 4-(2-chloroethoxy)benzaldehyde 

Downstream Products

• 1233250-86-6 C₄₈H₄₈Cl₆N₃O₁₂P₃ 

Relevant articles and documents

An efficient multigram-scale synthesis of 4-(ω-chloroalkoxy)phenols

Efficient multigram two-step syntheses of 4-(2-chloroethoxy)phenol and 4-(3-chloropropoxy)phenol in >70% yields starting from 4-hydroxybenzaldehyde and reagents with general formula Cl(CH2)nX (X = Cl, n = 2; X = OTs, n = 3) are proposed. 4-(2-Chloroethoxy)phenol can also be conveniently prepared from 4-methoxyphenol and 1,2-dichloroethane. The compounds thus obtained can be used in carbohydrate chemistry to synthesize glycosides bearing "universal" 4-(ω-chloroalkoxy)phenyl aglycons.

One step hair coloring compositions using salts

A hair coloring composition comprising the following two compositions which are mixed just prior to application to the hair: (a) a composition comprising a water-soluble peroxygen oxidizing agent; and (b) a composition comprising one or more oxidative hair coloring agents selected from the group consisting of an aromatic diamine, an amino phenol, a naphthol, a polyhydric phenol, a catechol and mixtures thereof; wherein the composition comprising one or more oxidative hair coloring agents further comprises al least one water soluble carbonate releasing salts; and optionally a water soluble ammonium salt, is described.

Enhanced color deposition for hair with sequestering agents

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