3383-74-2

Usage

InChI:InChI=1/C9H11ClO2/c1-11-8-2-4-9(5-3-8)12-7-6-10/h2-5H,6-7H2,1H3

Upstream product

• 150-76-5 4-methoxy-phenol 
• 107-06-2 1,2-dichloro-ethane 
• 107-04-0 1-Bromo-2-chloroethane 
• 3570-58-9 2-chloroethyl mesylate 

Downstream Products

• 114276-19-6 1-[2-(4-methoxy-phenoxy)-ethyl]-4-phenyl-piperidine-4-carboxylic acid ethyl ester 
• 101568-63-2 2-[2-(4-methoxy-phenoxy)-ethylamino]-ethanol 
• 4024-19-5 1-methoxy-4-(vinyloxy)benzene 
• 145276-56-8 6-<4-(4-methoxyphenoxyethyl)-1-piperazinyl>-3(2H)-pyridazinone 
• 10461-57-1 1-Allyloxy-3-[2-(4-methoxy-phenoxy)-ethylamino]-propan-2-ol 
• 10461-24-2 1-[2-(4-Methoxy-phenoxy)-ethylamino]-2-methyl-pentan-2-ol 
• 10450-25-6 [2-(3,4-Dimethoxy-phenyl)-ethyl]-[2-(4-methoxy-phenoxy)-ethyl]-amine 
• 281678-65-7 1,4-dibromo-2-(2-chloro-ethoxy)-5-methoxy-benzene 
• 100238-55-9 4-(2-chloroethoxy)phenol 
• 1417997-97-7 C₂₁H₂₄O₆ 
• 99355-75-6 5-methoxy-2,3-dihydrobenzofuran-6-carboxaldehyde 
• 25836-83-3 N-(2-(4-methoxyphenoxy)ethyl)aniline 

Relevant academic research and scientific papers

METHOD FOR PRODUCING POTASSIUM SALT, AND POTASSIUM SALT

PROBLEM TO BE SOLVED: To provide a method that makes it possible to efficiently produce a halogen compound useful as a precursor of a compound that can be used suitably for optical materials in general. SOLUTION: A method for producing potassium salt includes the step for producing potassium salt represented by formula (1) by the reaction between a compound represented by formula (3), a cyclic carbonate ester compound, and potassium carbonate. [R2 is an aromatic ring-containing group having C constituting an aromatic ring at a binding site to O; n is 1 or 2; R1 independently represents an alkylene group]. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

An efficient multigram-scale synthesis of 4-(ω-chloroalkoxy)phenols

Efficient multigram two-step syntheses of 4-(2-chloroethoxy)phenol and 4-(3-chloropropoxy)phenol in >70% yields starting from 4-hydroxybenzaldehyde and reagents with general formula Cl(CH2)nX (X = Cl, n = 2; X = OTs, n = 3) are proposed. 4-(2-Chloroethoxy)phenol can also be conveniently prepared from 4-methoxyphenol and 1,2-dichloroethane. The compounds thus obtained can be used in carbohydrate chemistry to synthesize glycosides bearing "universal" 4-(ω-chloroalkoxy)phenyl aglycons.

MANUFACTURING METHOD OF HALOGEN COMPOUND, MANUFACTURING METHOD OF POTASSIUM SALT AND POTASSIUM SALT

PROBLEM TO BE SOLVED: To provide a method capable of manufacturing a halogen compound useful as a precursor of a compound capable of being preferably used especially for optical system materials generally with high efficiency. SOLUTION: There is provided a manufacturing method of a halogen compound including a process of reacting a compound represented by the following formula (1) and a halogenation agent to produce a halogen compound represented by the following formula (2). In the formula (1), R1 is a linear or branched alkylene group, R2 is an aromatic ring-containing group having a carbon atom constituting an aromatic ring at a binding part with an oxygen atom represented in the formula, n is 1 or 2 and two of R1s may same or different when n is 2. In the formula (2), X is a halogen atom. COPYRIGHT: (C)2016,JPOandINPIT

Synthesis and Biological Evaluation of ortho-Aryl N-Hydroxycinnamides as Potent Histone Deacetylase (HDAC) 8 Isoform-Selective Inhibitors

Histone deacetylases (HDACs) are a family of enzymes that play a crucial role in biological process and diseases. In contrast to other isozymes, HDAC8 is uniquely incapable of histone acetylation. In order to delineate its physiological function, we devel

A practical approach to highly functionalized benzodihydrofurans

A number of aromatic dibromides have been treated with 2-3 equivalents of n-butyllithium in order to initiate two sequential chemical events, a Parham cyclization and an intermolecular reaction with DMF. (C) 2000 Elsevier Science Ltd.

Synthesis and pharmacological activity of some new pyridazinones

The synthesis of a series of piperazinyl-pyridazinones is reported. The blocking activity of these compounds was determined on the pre- and postsynaptic α-adrenoreceptors of isolated rat vas deferens. For compounds 7, 17 and 18, the hypotensive activity w