100252-56-0Relevant academic research and scientific papers
6-Substituted 2,4-diamino-5-methylpyrido[2,3-d]pyrimidines as inhibitors of dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents
Gangjee,Vasudevan,Queener,Kisliuk
, p. 1778 - 1785 (2007/10/02)
The synthesis and biological activity of 15 6-substituted 2,4-diamino-5- methylpyrido[2,3-d]-pyrimidines are reported. These compounds were synthesized in improved yields by modifications of procedures previously reported by us. Specifically, dimethoxyphe
