1002555-77-2

Upstream product

• 101-92-8 4'-Chloroacetoacetanilide 
• 100-46-9 benzylamine 
• 77871-53-5 C₁₇H₁₇ClN₂O 

Relevant academic research and scientific papers

Cu(TFA)2-catalyzed oxidative tandem cyclization/1,2-alkyl migration of enamino amides for synthesis of pyrrolin-4-ones

A novel Cu(TFA)2-catalyzed oxidative tandem cyclization/1,2- alkyl migration of readily available enamino amides for the synthesis of pyrrolin-4-ones has been developed. The reaction tolerates a wide range of functional groups and is a reliable method for the rapid synthesis of substituted pyrrolin-4-ones in high yields under mild conditions.

Efficient synthesis of highly substituted pyrrolin-4-ones via PIFA-mediated cyclization reactions of enaminones

A convenient and efficient synthesis of highly substituted pyrrolin-4-ones is developed via the PIFA-mediated cyclization reactions of readily available enaminones, and a mechanism involving sequential cleavage of N - C bond, formation of new N - C bond, intramolecular addition reaction, and benzilic acid type rearrangement is proposed.