1002789-86-7 Usage
Uses
Used in Pharmaceutical Industry:
TZ-9 is used as an anticancer agent for its ability to effectively inhibit the growth of cancer cells, making it a candidate for further development in targeted cancer therapies.
Used in Neuroprotection:
TZ-9 is used as a neuroprotective agent due to its potential to provide protection to the nervous system, which may be beneficial in treating neurodegenerative diseases.
Used in Anti-Inflammatory Applications:
TZ-9 is used as an anti-inflammatory agent, leveraging its potential to reduce inflammation, which could be advantageous in managing inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1002789-86-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,2,7,8 and 9 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1002789-86:
(9*1)+(8*0)+(7*0)+(6*2)+(5*7)+(4*8)+(3*9)+(2*8)+(1*6)=137
137 % 10 = 7
So 1002789-86-7 is a valid CAS Registry Number.
1002789-86-7Relevant academic research and scientific papers
Optimised synthesis of diamino-triazinylmethyl benzoates as inhibitors of Rad6B ubiquitin conjugating enzyme
Kothayer, Hend,Morelli, Matteo,Brahemi, Ghali,Elshanawani, Abdalla A.,Abu Kull, Mansour E.,El-Sabbagh, Osama I.,Shekhar, Malathy P.V.,Westwell, Andrew D.
, p. 7015 - 7018 (2015/01/09)
Recently, we have identified the first inhibitors of Rad6B, an E2 enzyme essential for post-replication DNA repair and a potential new drug target for the treatment of breast cancer. We report two newly optimised synthetic routes to our [4-amino-6-(phenylamino)-1,3,5-triazin-2-yl]methyl 4-nitrobenzoate target compounds TZ8 and TZ9 with general applicability for further structure-activity relationship studies around this pharmacophore. The key step involved the condensation/cyclisation between phenylbiguanide and either ethyl bromoacetate or dimethyloxalate in good yield.
